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Drug-Target Interaction

Drug

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PubChem ID:643985
Structure:
Synonyms:
()-(6s)-methadone
()-(s)-methadone
(+)-(6S)-Methadone
(+)-(S)-Methadone
(+)-Methadone
(6S)-6-(dimethylamino)-4,4-diphenylheptan-3-one
(6S)-Methadone
(s)-()-methadone
(S)-(+)-Methadone
(S)-6-(Dimethylamino)-4,4-diphenyl-3-heptanone
3-heptanone, 6-(dimethylamino)-4,4-diphenyl-, (6S)-
3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, (6S)- (9CI)
3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, (S)- (8CI)
5653-80-5
6S-Methadone
AC1LD8DL
CHEMBL350719
CID643985
d-6-(Dimethylamino)-4,4-diphenyl-3-heptanone
d-Methadone
Dextromethadone
L-(+)-Methadone
L-Methadone
methadone, ()-
Methadone, (+)-
S-(+)-Methadone
S-Methadone
Side-Effects:
Side-EffectFrequency
drug dependence0
ventricular fibrillation0
urticaria0
erythema0
tremor0
thrombocytopenia0
tachycardia0
syncope0
swelling0
sweating0
spasm0
sneezing0
shock0
seizures0
ventricular tachycardia0
vomiting0
weight gain0
rhinorrhea0
insomnia0
cardiomyopathy0
bradycardia0
dysphoria0
lightheadedness0
respiratory arrest0
urinary hesitancy0
hypomagnesemia0
agitation0
urinary retention0
dry mouth0
weight loss0
pulmonary edema0
pruritus0
edema0
abuse0
dizziness0
diarrhea0
decreased libido0
constipation0
confusion0
asthenia0
arrhythmia0
anxiety0
anorexia0
amenorrhea0
abdominal pain0
euphoria0
fever0
flushing0
phlebitis0
weakness0
palpitations0
nausea0
irritability0
hypotension0
hypokalemia0
chronic hepatitis0
heart failure0
cardiac arrest0
headache0
hallucinations0
glossitis0
abdominal cramps0

Target

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Uniprot ID:CP2CJ_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC17
CYPIIC19
Cytochrome P450 2C19
Mephenytoin 4-hydroxylase
P450-11A
P450-254C
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: