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Drug-Target Interaction

Drug

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PubChem ID:636806
Structure:
Synonyms:
3,5-pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, ethyl methyl ester
4-(2,3-dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic
4-(2,3-dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
72509-76-3
AC1LCSY4
CHEMBL254609
ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Felodipine
Lopac-F-9677
NCGC00015455-01
NCGC00015455-02
ZINC19802035
ATC-Codes:
Side-Effects:
Side-EffectFrequency
sexual dysfunction0.0010
postural hypotension0.0010
hypotension0.0010
salivary gland enlargement0.0010
urinary urgency0.0010
hepatitis0.0010
myalgia0.0010
impotence0.0010
flatulence0.0010
fever0.0010
dry mouth0.0010
vomiting0.0010
flu0.0010
pruritis0.0010
polyuria0.0010
syncope0.0010
tachycardia0.0010
tremor0.0010
nervousness0.0010
myocardial infarction0.0010
muscle cramps0.0010
urticaria0.0010
erythema nodosum0.0010
erythema multiforme0.0010
epistaxis0.0010
confusion0.0010
chest pain0.0010
leucocytoclastic vasculitis0.0010
insomnia0.0010
arthralgia0.0010
arrhythmia0.0010
anxiety0.0010
angioedema0.0010
angina pectoris0.0010
anemia0.0010
abdominal pain0.0010
urinary frequency0.0010
bradycardia0.0010
photosensitivity0.0010
diarrhea0.0010
edema0.0010
somnolence0.0010
dysuria0.0010
dyspnea0.0010
regurgitation0.0010
knee pain0
bronchitis0
peripheral edema0
erythema0
rhinorrhea0
upper respiratory tract infection0
arm pain0
sneezing0
sinusitis0
foot pain0
rash0
dyspepsia0
dizziness0
decreased libido0
cough0
constipation0
back pain0
gynecomastia0
headache0
hip pain0
pharyngitis0
paresthesia0
palpitations0
nausea0
leg pain0
irritability0
infection0
flushing0
asthenia0

Target

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Uniprot ID:CALM_HUMAN
Synonyms:
Calmodulin
CaM
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:1AJI 1CDL 1CLL 1CTR 1IWQ 1J7O 1J7P 1K90 1K93 1L7Z 1LVC 1NKF 1PK0 1S26 1SK6 1SW8 1WRZ 1XFU 1XFV 1XFW 1XFX 1XFY 1XFZ 1Y6W 1YR5 1YRT 1YRU 1ZOT 1ZUZ 2BE6 2F3Y 2F3Z 2HF5 2I08 2JZI 2K0E 2K0F 2K0J 2K61 2R28 2V01 2V02 2VAY 2W73 2WEL 3BYA 3DVE 3DVJ 3DVK 3DVM 3G43 3HR4
Structure:
3HR4

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: