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Drug-Target Interaction

Drug

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PubChem ID:6133
Structure:
Synonyms:
2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-.beta.-D-ribofuranosyl]-
4-24-00-01222 (Beilstein Handbook Reference)
5'-UTP
63-39-8
AC1L1LV9
AC1Q1I4F
AIDS-222065
AIDS222065
AR-1L8074
bmse000295
BRN 0071520
BSPBio_003192
C00075
C9H15N2O15P3
CHEBI:15713
CHEMBL336296
DC99D596-4755-4E87-B3AA-F1D6CFEDCE9A
DivK1c_000269
EINECS 200-558-7
H4utp
IDI1_000269
INS316
INS365 Ophthalmic Solution
KBio1_000269
KBio2_002177
KBio2_004745
KBio2_007313
KBio3_002692
KBioGR_001481
KBioSS_002177
LS-160841
MolPort-006-110-165
NCGC00163323-01
NChemBio.2007.9-comp22
NINDS_000269
SPBio_000509
Spectrum2_000525
Spectrum3_001596
Spectrum4_000851
Spectrum5_001167
Spectrum_001697
Uridine 5'-(tetrahydrogen triphosphate)
Uridine 5'-(tetrahydrogen triphosphate) (8CI,9CI)
Uridine 5'-triphosphate
Uridine 5'-triphosphoric acid
uridine tetrahydrogen triphosphate
Uridine triphosphate
Uridine, 5'-(tetrahydrogen triphosphate)
Uridine, mono(tetrahydrogen triphosphate) (ester)
Uteplex
UTP
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]metho
[[[5-(2,4-Dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid

Target

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Uniprot ID:POLG_HCVBK
Synonyms:
Genome polyprotein
EC-Numbers:-
Organism:HCV
Hepatitis C virus genotype 1b
isolate BK
PDB IDs:1A1Q 1BT7 1C2P 1CSJ 1CU1 1GX5 1GX6 1JXP 1NHU 1NHV 1NS3 1OS5 1QUV 2AWZ 2AX0 2AX1 2BRK 2BRL 2DXS 2GIQ 2GIR 2HAI 2HWH 2HWI 2I1R 2JC0 2JC1 2O5D 2WHO 2ZKU 3BR9 3BSA 3BSC 3CDE 3CIZ 3CJ0 3CJ2 3CJ3 3CJ4 3CJ5 3CO9 3CVK 3CWJ 3D28 3D5M 3FQK 3FRZ 8OHM
Structure:
8OHM

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: