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Drug-Target Interaction

Drug

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PubChem ID:60879
Structure:
Synonyms:
4-[[2-butyl-5-[3-hydroxy-3-oxo-2-(thiophen-2-ylmethyl)prop-1-enyl]imidazol
4-[[2-butyl-5-[3-hydroxy-3-oxo-2-(thiophen-2-ylmethyl)prop-1-enyl]imidazol-1-yl]methyl]benzoic acid
AC1L1U3O
CID60879
DB00876
Eprosartan
ATC-Codes:
Side-Effects:
Side-EffectFrequency
upper respiratory tract infection0.07
pharyngitis0.036666665
rhinitis0.036666665
coughing0.036666665
fatigue0.016666666
infection viral0.016666666
arthralgia0.016666666
abdominal pain0.016666666
urinary tract infection0.0066666664
hypertriglyceridemia0.0066666664
dizziness0.0010
muscle pain0.0010
muscle weakness0.0010
angioedema0.0010
urticaria0.0010
asthenia0.0010
rash0.0010
swelling0.0010
headaches0.0010
rhabdomyolysis0.0010
hypotension0.0010
postural hypotension0.0010
myositis0.0010
cardiac insufficiency0.0010
pruritus0.0010
renal failure0.0010
tachycardia0
dyspepsia0
ischemia0
peripheral edema0
asthma0
palpitations0
hyperkalemia0
tendinitis0
urinary frequency0
influenza0
nervousness0
tremor0
cystitis0
malaise0
allergic reaction0
gout0
constipation0
paresthesia0
hematuria0
anorexia0
migraine0
polyuria0
otitis externa0
thrombocytopenia0
angina pectoris0
arthritis0
insomnia0
vomiting0
anxiety0
increased sweating0
toothache0
dyspnea0
somnolence0
neuritis0
periodontitis0
arthrosis0
otitis media0
epistaxis0
albuminuria0
neutropenia0
leg cramps0
hypercholesterolemia0
gastritis0
chest pain0
pain0
abnormal vision0
herpes simplex0
nausea0
syncope0
eczema0
conjunctivitis0
gastroenteritis0
anemia0
back pain0
fever0
esophagitis0
urinary incontinence0
chest pain substernal0
bone pain0
furunculosis0
dry mouth0
bradycardia0
atrial fibrillation0
hypokalemia0
edema0
hyponatremia0
ataxia0
vertigo0
diarrhea0
tinnitus0
diabetes mellitus0
bronchitis0
hyperglycemia0
hypersensitivity0
glycosuria0
flushing0
leukopenia0
ecg abnormal0
gingivitis0
sinusitis0
purpura0
flatulence0
kidney calculus0

Target

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Uniprot ID:CP2C9_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC9
Cytochrome P450 2C9
P-450MP
P450 MP-4/MP-8
P450 PB-1
S-mephenytoin 4-hydroxylase
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:1OG2 1OG5 1R9O
Structure:
1R9O

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: