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Drug-Target Interaction

Drug

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PubChem ID:6030
Structure:
Synonyms:
1loq
1xz8
2,4(1H,3H)-pyrimidinedione, 1-(5-O-phosphono-beta-D-ribofuranosyl)-
25618-56-8
27416-86-0
5'-UMP
5'-URIDYLIC ACID
5'-uridylic acid (8CI)(9CI)
5'-Uridylic acid, homopolymer
5'Uridylic acid
5-24-06-00173 (Beilstein Handbook Reference)
53624-79-6
58-97-9
81795-92-8
81795-93-9
954D2AA9-0360-4F63-A7BF-63254220F1F3
AC1L1LNC
AC1Q1I4H
AIDS-221902
AIDS221902
AR-1G9590
bmse000280
BRN 0047486
C00105
CHEBI:16695
CHEMBL214393
EINECS 200-408-0
H2U
LS-160843
LS-187795
NCGC00163325-01
POLY U
Polyuridylic acid
Polyuridylic acids
pU
U 5'-P
U25
U5P
UDP
UMP
UMP (nucleic acid)
Uracil polynucleotides
Uridine 5'-(dihydrogen phosphate)
Uridine 5'-monophosphate
Uridine 5'-phosphate
Uridine 5'-phosphoric acid
Uridine monophosphate
Uridine phosphate
Uridine, mono(dihydrogen phosphate) (ester)
URIDINE-5'-MONOPHOSPHATE
uridine-phosphate
uridylate
Uridylic acid
Uridylic acid (6CI)
[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl

Target

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Uniprot ID:PYRF_METTH
Synonyms:
OMP decarboxylase
OMPDCase
OMPdecase
Orotidine 5'-phosphate decarboxylase
EC-Numbers:4.1.1.23
Organism:Methanobacterium thermoautotrophicum
PDB IDs:1DV7 1DVJ 1KLY 1KLZ 1KM0 1KM1 1KM2 1KM3 1KM4 1KM5 1KM6 1LOL 1LOQ 1LOR 1LOS 1LP6 1X1Z 2E6Y 2ZZ1 2ZZ2 2ZZ3 2ZZ4 2ZZ5 2ZZ6 2ZZ7 3G18 3G1A 3G1D 3G1F 3G1H 3G1S 3G1V 3G1X 3G1Y 3G22 3G24
Structure:
3G24

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: