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Drug-Target Interaction

Drug

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PubChem ID:6013
Structure:
Synonyms:
"testosterone; 4-androsten-17?-ol-3-one; 17?-hydroxy-4-androsten-3-one"
(17beta)-17-Hydroxyandrost-4-en-3-one
(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,
(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
17-beta-Hydroxy-delta(sup 4)-androsten-3-one
17-beta-Hydroxyandrost-4-en-3-one
17-Hydroxy-(17-beta)-androst-4-en-3-one
17-Hydroxy-(17beta)-androst-4-en-3-one
17?-Hydroxy-4-androsten-3-one
17b-hydroxy-4-androsten-3-one
17beta-Hydroxy-3-oxo-4-androstene
17beta-Hydroxy-4-androsten-3-one
17beta-Hydroxy-delta(sup4)-androsten-3-one
17beta-Hydroxyandrost-4-en-3-one
17beta-Hydroxyandrost-4-ene-3-one
4-Androsten-17?-ol-3-one
4-androsten-17beta-ol-3-one
4-androstene-17beta-ol-3-one
46923_FLUKA
46923_RIEDEL
58-22-0
7-beta-Hydroxyandrost-4-en-3-one
9-beta,10-alpha-ANDROST-4-EN-3-ONE, 17-beta-HYDROXY-
AA 2500
AC-14899
AC1L1LM0
AIDS-070519
AIDS070519
Andro
Andro 100
Androderm
Androderm (TN)
AndroGel
Androgel (TN)
Android
Androlin
Andronaq
Andronate 100
Andronate 200
Andropatch
Andropository 200
Androsorb
Androst-4-en-17beta-ol-3-one
Androst-4-en-3-one, 17-beta-hydroxy-
Androst-4-en-3-one, 17-hydroxy, (17.beta.)-
Androst-4-en-3-one, 17-hydroxy-, (17-beta)-
Androst-4-en-3-one, 17-hydroxy-, (17beta)-
Androst-4-en-3-one, 17beta-hydroxy-
Andrusol
Andryl 200
B5DEE83F-632B-48A1-A0ED-A51E7F13DF2E
BB_NC-0117
beta testosterone
BIDD:ER0555
BIM-0061761.0001
Bio-0678
C00535
c1014
C19H28O2
CCG-101189
CCRIS 574
CDB 111C
CHEBI:17347
CHEMBL386630
CMC_13449
COL 1621
CP 601B
CPD000058344
Cristerona T
Cristerone T
D00075
DB00624
DEA No. 4000
delta(sup 4)-Androsten-17(beta)-ol-3-one
delta4-androsten-17b-ol-3-one
delta4-Androsten-17beta-ol-3-one
Depo-Testadiol
Depotest
DHT
EINECS 200-370-5
Everone 200
Geno-cristaux gremy
Halotensin
HMS2052N11
HMS2272B03
HMS2272P03
Homosteron
Homosterone
HSDB 3398
Intrinsa
LibiGel
LMST02020002
LS-148813
Malerone
Malestrone (amps)
Malogen in Oil
Malogen, aquaspension injection
Mertestate
MLS000563091
MLS001032098
MLS001306401
MLS002174283
NCGC00091018-01
nchem.1113-comp1
Neo-Hombreol F
Neo-testis
Neotestis
NSC 9700
Oreton
Oreton F
Oreton-F
Orquisteron
Perandren
Percutacrine androgenique
Primotest
Primoteston
Relibra
S00309
S2033_Selleck
SAM001246921
Scheinpharm Testone-Cyp
SMR000058344
SMR001261453
Striant
Striant (TN)
Sustanon
Sustanone
Sustason 250
Synandrol F
T-Cypionate
T1500_SIGMA
T5411_FLUKA
T5411_SIGMA
TES
Teslen
Testamone 100
Testandrone
Testaqua
Testex
Testiculosterone
Testim
Testim (TN)
Testobase
Testoderm
TESTODERM TTS
Testogel
Testoject-50
Testolin
Testopel Pellets
Testopropon
Testosteroid
Testosteron
Testosterona
Testosterona [INN-Spanish]
Testosterone
Testosterone (JAN/USP)
Testosterone and its esters
Testosterone Cypionate
Testosterone Enanthate
Testosterone hydrate
Testosterone solution
Testosterone [Androgenic steroids, anabolic]
Testosterone [BAN:INN]
Testosterone [INN:BAN]
Testosterone-Supplied by Selleck Chemicals
Testosterone; 4-Androsten-17?-ol-3-one; 17?-Hydroxy-4-androsten-3-one
Testosteronum
Testosteronum [INN-Latin]
Testostosterone
Testoviron
Testoviron schering
Testoviron T
Testred
Testred Cypionate 200
Testrin-P.A
Testro AQ
Testrone
Testryl
TheraDerm
TMTDS
trans-Testosterone
UNII-3XMK78S47O
Virilon
Virilon IM
Virormone
Virosterone
ZINC06500184
ATC-Codes:
Side-Effects:
Side-EffectFrequency
pruritus0.08135714
lab test abnormal0.047799997
contact dermatitis0.04
gum pain0.031
blister0.028461538
anemia0.025
acne0.022789473
skin dry0.019
erythema0.01692308
peripheral edema0.015000001
headache0.01395652
nervousness0.013333333
asthenia0.013333333
gynecomastia0.0066999993
blood pressure increased0.0066666664
mastodynia0.0064285705
decreased libido0.005933334
gastrointestinal bleeding0.0057500005
rash0.005384616
flushes0.0050
benign prostatic hyperplasia0.0050
hypertension0.004999999
edema0.002727273
prostate carcinoma0.0023750002
insomnia0.0021428573
alopecia0.0016956517
personality disorder0.0010
hypersensitivity reaction0.0010
hepatic neoplasms0.0010
nausea0.0010
elevated cholesterol0.0010
impotence0.0010
mediastinal disorders0.0010
renal disorders0.0010
polycythemia0.0010
glucose tolerance impaired0.0010
myalgia0.0010
malaise0.0010
abnormal liver function tests0.0010
weight increase0.0010
vascular disorders0.0010
urticaria0.0010
incontinence0.0010
sleep apnea0.0010
vomiting0.0010
serum sickness0.0010
seborrhea0.0010
peliosis0.0010
priapism0.0010
allergic reaction0.0010
confusion0.0010
epididymitis0.0010
anxiety0.0010
arthralgia0.0010
endocrine disorders0.0010
dizziness0.0010
dysuria0.0010
dyspnea0.0010
diarrhea0.0010
abdominal pain0.0010
dermatitis0.0010
testicular atrophy0.0010
carcinoma0.0010
breast disorder0.0010
fatigue0.0010
hepatoma0.0010
hematuria0.0010
bleeding0.0010
connective tissue disorders0.0010
hirsuitism0.0010
adenomas0
clotting0
deep thrombophlebitis0
deep vein thrombosis0
emotional lability0
urinary urgency0
chills0
peripheral vascular disorder0
urinary retention0
dry mouth0
memory loss0
cognitive dysfunction0
depressed mood0
apnea0
angina pectoris0
asthma0
anger0
penile pain0
abdominal cramps0
amnesia0
urinary hesitancy0
prostatic specific antigen increase0
skin irritation0
amenorrhea0
migraine0
cerebral hemorrhage0
masculinization0
pelvic pain0
paresthesia0
pain0
nocturia0
gingivitis0
heart disease0
leukoplakia0
leukopenia0
jaundice0
irritability0
infection0
hypokalemia0
breast enlargement0
pneumonia0
polyps0
habituation0
vertigo0
scarring0
varicocele0
urinary tract infection0
hyperlipidemia0
coronary artery disease0
ulcer0
toothache0
sweating0
stomatitis0
cyst0
seizures0
renal failure0
hypertriglyceridemia0

Target

show target details
Uniprot ID:SHBG_HUMAN
Synonyms:
ABP
SBP
Sex hormone-binding globulin
Sex steroid-binding protein
SHBG
TeBG
Testis-specific androgen-binding protein
Testosterone-estradiol-binding globulin
Testosterone-estrogen-binding globulin
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:1D2S 1F5F 1KDK 1KDM 1LHN 1LHO 1LHU 1LHV 1LHW
Structure:
1LHW

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: