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Drug-Target Interaction

Drug

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PubChem ID:5743
Structure:
Synonyms:
(11beta,16alpha)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,
(11beta,16alpha)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
(11beta,16alpha)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione labeled with tritium
(3H)-Dexamethasone
(3H)-Dexamethasone (labeled with tritium)
(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16-alpha-methyl-9-alpha-fluorohydrocortisone
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
137098-19-2
16-.alpha.-Methyl-9-.alpha.-fluoro-1,4-pregnadiene-11-.beta.,17-.alpha.,21-triol-3,20-dione
16-alpha-Methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20-dione
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-11-beta,17-alpha,21-trihydroxypregna-1,4-diene-3,20-dione
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-.delta.(sup1)-hydrocortisone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoro-11.beta.-17.alpha.-21-trihydroxypregna-1,4-diene-3,20-dione
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
23495-06-9
31375_FLUKA
4-alpha-Fluoro-16-alpha-methyl-11-beta,17,21-trihydroxypregna-1,4-diene-3,20-dione
4.alpha.-Fluoro-16.alpha.-methyl-11.beta.-17,21-trihydroxypregna-1,4-diene-3,20-dione
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-alpha-Fluoro-16-alpha-methyl-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20-dione
9-alpha-Fluoro-16-alpha-methylprednisolone
9-Fluoro-11-beta,17,21-trihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11.beta.,17,21-trihydroxy-16.alpha.-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-11.beta.-17.alpha.- 21-trihydroxy-16.alpha.-methylpregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-16.alpha.-methyl-1,4-pregnadiene-11.beta.-17-.alpha.-21-triol-3,20-dione
9.alpha.-Fluoro-16.alpha.-methyl-11.beta.,17.alpha.,21.beta.-trihydroxy-pregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-16.alpha.-methylprednisolone
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha-Fluoro-16alpha-methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
9alpha-Fluoro-16alpha-methylprednisolone
Aeroseb-D
Aeroseb-Dex
AI3-50934
Anaflogistico
Aphtasolon
Auxiron
Azimycin (Veterinary)
Azium
Azium (Veterinary)
Bisu DS
BSPBio_000995
C15643
C22H29FO5
Calonat
CCRIS 7067
CHEBI:41879
component of Dronactin
Corson
Corsone
Cortisumman
D00292
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron-LA
Decagel
Decalix
Decasone
Decaspray
Dectancyl
Dekacort
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desamethasone
Desameton
Deseronil
DEX
Dex-ide
Dexa Mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexametasona
Dexametasona [INN-Spanish]
Dexameth
Dexamethansone
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone alcohol
Dexamethasone Base
DEXAMETHASONE INTENSOL
Dexamethasone sodium phosphate
Dexamethasone [BAN:INN:JAN]
Dexamethasone [INN:BAN:JAN]
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
DEXASPORIN
Dexinolon
Dexinoral
Dexone
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
Dextelan
Dezone
Dinormon
DRG-0013
DXM
DXMS
EINECS 200-003-9
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Fulvidex (Veterinary)
Gammacorten
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
HL-Dex
HSDB 3053
Isopto-Dex
Lokalison F
Loverine
LS-7300
Luxazone
Maxidex
Maxidex (TN)
Maxitrol
Mediamethasone
Methylfluorprednisolone
Mexidex
Millicorten
Mixture Name
MK 125
MLS001055412
MLS001332507
MLS001332508
MolMap_000018
MYMETHASONE
Naquasone (Veterinary)
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
nchembio809-comp2
NCI60_003067
NEOMYCIN AND POLYMYXIN B SULFATES AND DEXAMETHASONE
NSC 34521
NSC34521
Ocu-trol
Oradexon
Pet Derm III
Policort
Prednisolon F
Prednisolone F
Prednisolone, 9.alpha.-fluoro-16.alpha.-methyl-
Prednisolone, 9alpha-fluoro-16alpha-methyl-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11.beta.,16.alpha.)-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11beta,16alpha)-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, labeled with tritium, (11beta,16alpha)-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11.beta.,17,21-trihydroxy-16.alpha.-methyl-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-
ProDex
SGCUT00126
SK-Dexamethasone
SMP1_000092
SMR000857119
SMR001227192
Spectrum5_002019
Spoloven
ST5307091
Sunia Sol D
Superprednol
TL8003317
Tobradex
TOBRAMYCIN AND DEXAMETHASONE
to_000038
Tresaderm (Veterinary)
Turbinaire
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
ATC-Codes:

Target

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Uniprot ID:PGH2_SHEEP
Synonyms:
COX-2
Cyclooxygenase-2
PGH synthase 2
PGHS-2
PHS II
Prostaglandin G/H synthase 2
Prostaglandin H2 synthase 2
Prostaglandin-endoperoxide synthase 2
EC-Numbers:1.14.99.1
Organism:Ovis aries
Sheep
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
-->25000-

References: