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Drug-Target Interaction

Drug

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PubChem ID:55918
Structure:
Synonyms:
3(2H)-Pyridazinone, 4,5-dihydro-6-(4-(1H-imidazol-1-yl)phenyl)-
3-(4-imidazol-1-ylphenyl)-4,5-dihydro-1H-pyridazin-6-one
4,5-dihydro-6-(4-(1H-imidazol-1-yl)phenyl)-3(2H)-pyridazinone
4,5-Dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinone
84243-58-3
89198-09-4
89198-09-4 (hydrochloride)
AC1L1K2C
C13H12N4O
CCG-204726
CHEBI:111220
CHEMBL12831
CI 914
CI-914
Cl 914
EU-0100639
HMS2233L24
HMS3261P20
I 0782
I0782_SIGMA
IMAZODAN
Imazodan [INN]
Imazodanum
Imazodanum [Latin]
Lopac-I-0782
Lopac0_000639
LS-177806
MLS000862182
NCGC00015547-01
NCGC00015547-02
NCGC00015547-03
NCGC00015547-04
NCGC00094006-01
NCGC00094006-02
SMR000326945
ZINC00001553

Target

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Uniprot ID:PDE2A_HUMAN
Synonyms:
cGMP-dependent 3',5'-cyclic phosphodiesterase
CGS-PDE
cGSPDE
Cyclic GMP-stimulated phosphodiesterase
EC-Numbers:3.1.4.17
Organism:Homo sapiens
Human
PDB IDs:1Z1L
Structure:
1Z1L

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--500000-
--760000-
--800000-

References: