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Drug-Target Interaction

Drug

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PubChem ID:5494449
Structure:
Synonyms:
()-oxazepam hemisuccinate sodium salt
2f4j
639089-54-6
Cyclopropanecarboxamide, N-(4-((4-(4-methyl-1-piperazinyl)-6-((5-methyl-1H-pyrazol-3-yl)amino)-2-pyrimidinyl)thio)phenyl)-
Cyclopropanecarboxylic Acid
Cyclopropanecarboxylic acid N-(4-((4-(4-methylpiperazin-1-yl)-6-(5-methyl-2H-pyrazol-3-ylamino)pyrimidin-2-yl)sulfanyl)phenyl)amide
L-001281814
MK-0457
MLS001065920
N-(4-(4-(3-methyl-1H-pyrazol-5-ylamino)-6-(4-methylpiperazin-1-yl)pyrimidin-2-ylthio)phenyl)cyclopropanecarboxamide
SMR000486395
Tozasertib
VX-680
VX6

Target

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Uniprot ID:MK10_HUMAN
Synonyms:
c-Jun N-terminal kinase 3
MAP kinase p49 3F12
Mitogen-activated protein kinase 10
Stress-activated protein kinase JNK3
EC-Numbers:2.7.11.24
Organism:Homo sapiens
Human
PDB IDs:1JNK 1PMN 1PMQ 1PMU 1PMV 2B1P 2EXC 2O0U 2O2U 2OK1 2P33 2R9S 2WAJ 2ZDT 2ZDU 3CGF 3CGO 3DA6 3FI2 3FI3 3FV8 3G90 3G9L 3G9N
Structure:
3G9N

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
-2800--

References: