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Drug-Target Interaction

Drug

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PubChem ID:5493444
Structure:
Synonyms:
(2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4
(2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide
173334-57-1
AC1NUU28
Aliskiren
Aliskiren (USAN/INN)
Aliskiren [INN]
C41
CHEBI:601027
CHEMBL1639
D03208
DB01258
NCGC00186464-01
Rasilez
Rasilez (TN)
SPP 100
SPP100
Tekturna
ATC-Codes:
Side-Effects:
Side-EffectFrequency
headache0
peripheral edema0
bronchitis0
gastroesophageal reflux0
diarrhea0
cancer0
vertigo0
asthenia0
dyspepsia0
seizures0
spasm0
allergic reaction0
rhabdomyolysis0
upper respiratory tract infection0
arthralgia0
loss of consciousness0
nausea0
pain in limb0
pain0
insomnia0
swelling0
fatigue0
cough0
nasopharyngitis0
shoulder pain0
rhinitis0
angioedema0
constipation0
back pain0
rash0
neck pain0
epistaxis0
anemia0
influenza0
abdominal pain0
dizziness0
edema0
urinary tract infection0
hemorrhage0
myositis0
gout0

Target

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Uniprot ID:RENI1_MOUSE
Synonyms:
Angiotensinogenase
Kidney renin
Renin-1
EC-Numbers:3.4.23.15
Organism:Mouse
Mus musculus
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--4.5-

References: