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Drug-Target Interaction

Drug

show drug details
PubChem ID:54841
Structure:
Synonyms:
(-)-Tomoxetine
(3R)-N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine
83015-26-3
AC-5316
AC1L1HTI
AC1Q57N5
Atomoxetine
Atomoxetine (INN)
Benzenepropanamine, N-methyl-gamma-(2-methylphenoxy)-, (gammaR)-
BRD-K20141153-003-03-8
CHEBI:127342
CHEMBL641
D07473
DB00289
HSDB 7352
LS-187331
NCGC00025345-01
PDSP1_000504
PDSP2_000502
Tocris-2011
Tomoxetina
Tomoxetina [Spanish]
Tomoxetine
Tomoxetine Hydrochloride (CAS 82248-59-7) (-) (R) Tomoxetine is CAS 83015-26-3 (-)
Tomoxetine [INN]
Tomoxetinum
Tomoxetinum [Latin]
UNII-ASW034S0B8
ATC-Codes:
Side-Effects:
Side-EffectFrequency
headache0.21499999
abdominal pain upper0.13333334
abdominal pain0.116666675
insomnia0.116666675
cough0.09
dry mouth0.08
nausea0.07882352
vomiting0.07571428
somnolence0.060000002
fatigue0.052500002
sinusitis0.049999997
dysmenorrhea0.046666667
vertigo0.044999998
hot flush0.044999998
urinary retention0.04
urinary hesitation0.04
dizziness0.038999997
dyspepsia0.038333338
libido decreased0.036666665
diarrhea0.035
rhinorrhea0.035
constipation0.033999998
paraesthesia0.029999997
sleep disorder0.026666665
pyrexia0.025
hyperhidrosis0.024999999
myalgia0.024999999
menstrual disorder0.024999999
sweating increased0.024999999
dermatitis0.023333333
palpitations0.023333332
sinus headache0.02
influenza0.02
ear infection0.02
chills0.02
anorexia0.02
flushes0.02
flatulence0.015
rash0.015
prostatitis0.015
impotence0.015
dysuria0.015
weight decreased0.011999999
tremor0.01
menstruation irregular0.01
seizure0.0010
syncope0.0010
seizure disorders0.0010
pelvic pain0.0010
vascular disorders0.0010
major depressive disorder0
feeling abnormal0
gastroenteritis viral0
emotional lability0
depressive symptoms0
elevated blood pressure0
sinus congestion0
tearfulness0
depressed mood0
dysphoria0
sore throat0
cold extremities0
liver function tests abnormal0
upper respiratory tract infection0
mediastinal disorders0
irritability0
infection0
heart disease0
enuresis0
conjunctivitis0
chest pain0
breast disorders0
back pain0
asthenia0
arthralgia0
nasal congestion0
nasopharyngitis0
nervousness0
loss of consciousness0
testicle pain0
sinus tachycardia0
tachycardia0
suicide attempt0
streptococcal pharyngitis0
sexual dysfunction0
pruritus0
pms0
pharyngitis0
pain0
anxiety0

Target

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Uniprot ID:Q6XP50_HUMAN
Synonyms:
Cytochrome P450
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: