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Drug-Target Interaction

Drug

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PubChem ID:54688
Structure:
Synonyms:
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[4-(dimethylamino)-3-hydroxy-6-methy
6-O-Methylerythromycin
6-O-Methylerythromycin A
81103-11-9
A-56268
Abbotic
Abbott-56268
AC1L1HJO
AC1Q6O1T
Adel
Astromen
Biaxin
Biaxin filmtab
Biaxin HP
Biaxin XL
Biaxin xl filmtab
Bicrolid
CCRIS 8833
CHEBI:136451
CHEMBL143
CID54688
Clacine
Clambiotic
Claribid
Claricide
Clarith
CLARITHROMYCIN
Clarithromycin extended release
Clarithromycin [USAN:BAN:INN:JAN]
Clarithromycine
Clarithromycine [INN-French]
Clarithromycinum
Clarithromycinum [INN-Latin]
Claritromicina
Claritromicina [INN-Spanish]
Clathromycin
Cyllid
DRG-0099
Erythromycin, 6-O-methyl-
Helas
Heliclar
Klacid
Klaciped
Klaricid
Klaricid H.P.
Klaricid Pediatric
Klarid
Klarin
Klax
Kofron
Mabicrol
Macladin
Maclar
Mavid
Naxy
TE-031
UNII-H1250JIK0A
Veclam
Zeclar
Side-Effects:
Side-EffectFrequency
hypoglycemia0.0010
pancytopenia0.0010
pharyngitis0.0010
pneumonia0.0010
polyps0.0010
psychosis0.0010
purpura0.0010
thrombotic thrombocytopenic purpura0.0010
rhinitis0.0010
stevens - johnson syndrome0.0010
pancreatitis0.0010
pain0.0010
otitis media0.0010
influenza0.0010
jaundice0.0010
leukopenia0.0010
mediastinal disorders0.0010
nausea0.0010
neoplasms0.0010
interstitial nephritis0.0010
neutropenia0.0010
nightmares0.0010
stomatitis0.0010
thrombocytopenia0.0010
tremor0.0010
alkaline phosphatase increased0.0010
aspartate aminotransferase increased0.0010
acute otitis media0.0010
increased white blood cell count0.0010
increased platelet count0.0010
insomnia0.0010
pseudomembranous colitis0.0010
infestation0.0010
allergic reactions0.0010
abnormal liver function tests0.0010
lactate dehydrogenase increased0.0010
amylase increased0.0010
urticaria0.0010
vascular disorders0.0010
ventricular tachycardia0.0010
vertigo0.0010
dry mouth0.0010
urinary retention0.0010
chills0.0010
hepatic failure0.0010
agitation0.0010
renal insufficiency0.0010
hypersensitivity0.0010
diarrhea0.0010
breast disorders0.0010
candidiasis0.0010
oral moniliasis0.0010
confusion0.0010
asthenia0.0010
conjunctivitis0.0010
connective tissue disorders0.0010
constipation0.0010
convulsions0.0010
cough0.0010
back pain0.0010
asthma0.0010
acquired immune deficiency syndrome0.0010
agranulocytosis0.0010
albuminuria0.0010
anaphylaxis0.0010
anemia0.0010
aplastic anemia0.0010
hemolytic anemia0.0010
anorexia0.0010
anxiety0.0010
arrhythmias0.0010
cysts0.0010
deafness0.0010
glycosuria0.0010
hallucinations0.0010
hay fever0.0010
headache0.0010
cardiac disorders0.0010
hematuria0.0010
hepatitis0.0010
hiv disease0.0010
bilirubinemia0.0010
hyperlipemia0.0010
glossitis0.0010
flatulence0.0010
fever0.0010
dyspepsia0.0010
dyspnea0.0010
eosinophilia0.0010
toxic epidermal necrolysis0.0010
erythema multiforme0.0010
rash0.0010
diaper rash0.0010
tinnitus0.001
infections0.001
hearing loss0.001
abdominal pain0.001
dizziness0.001
vomiting0.001
manic0
somnolence0
dysmenorrhea0
tachycardia0
nervousness0
vaginal moniliasis0
hepatomegaly0
seizures0
hyperhidrosis0
chest pain0
pruritus0
depersonalization0

Target

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Uniprot ID:CP2CJ_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC17
CYPIIC19
Cytochrome P450 2C19
Mephenytoin 4-hydroxylase
P450-11A
P450-254C
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: