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Drug-Target Interaction

Drug

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PubChem ID:5462516
Structure:
Synonyms:
(1R,2R,4R,6S,7R,8R,10R,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydro
191114-48-4
AC1NUWEH
C12009
D01078
HMR-3647
HMR3647
Ketek
Ketek (TN)
RU-66647
RU66647
TEL
Telithromycin
Telithromycin (JAN/USAN/INN)
ATC-Codes:
Side-Effects:
Side-EffectFrequency
nausea0.059
diarrhea0.055875003
headache0.0395
dizziness0.02675
vertigo0.026749998
vomiting0.022250002
palpitations0.0010
hepatic necrosis0.0010
loss of consciousness0.0010
syncope0.0010
edema0.0010
allergic reactions0.0010
toxic epidermal necrolysis0.0010
hepatitis0.0010
hepatic failure0.0010
stevens johnson syndrome0.0010
jaundice0.0010
anaphylaxis0.0010
angioedema0.0010
muscle cramps0.0010
myasthenia gravis0.0010
arrhythmias0.0010
pancreatitis0.0010
leukopenia0
polyuria0
paresthesia0
fungal infection0
bradycardia0
nervousness0
neutropenia0
nightmares0
pain0
pruritus0
stomatitis0
thrombocythemia0
increased sweating0
blurred vision0
disturbance in attention0
abdominal pain upper0
alkaline phosphatase increased0
ulcerative stomatitis0
liver function tests abnormal0
mouth ulceration0
peripheral edema0
dry mouth0
vascular disorders0
vaginitis0
urticaria0
insomnia0
hypotension0
vaginal moniliasis0
colitis0
connective tissue disorders0
constipation0
atopic dermatitis0
diplopia0
somnolence0
drug hypersensitivity0
oral moniliasis0
bundle branch block0
abdominal pain0
anemia0
anorexia0
anxiety0
asthenia0
back pain0
clotting0
breast disorders0
dysmenorrhea0
dyspepsia0
gastroesophageal reflux0
glossodynia0
glossitis0
heart disease0
rash0
hyperkalemia0
hypersensitivity0
hypokalemia0
gastroenteritis0
gastritis0
eczema0
eosinophilia0
eructation0
erythema multiforme0
reflux esophagitis0
fatigue0
flatulence0
flushing0
abdominal distention0

Target

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Uniprot ID:CP1A2_HUMAN
Synonyms:
CYPIA2
Cytochrome P450 1A2
P(3)450
P450 4
P450-P3
EC-Numbers:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:2HI4
Structure:
2HI4

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: