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Drug-Target Interaction

Drug

show drug details
PubChem ID:5426
Structure:
Synonyms:
( inverted question
( inverted question mark)-Thalidomide
()-thalidomide
(+)-Thalidomide
(+-)-N-(2,6-Dioxo-3-piperidyl)phthalimide
(+-)-Thalidomide
(+/-)-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
(+/-)-N-(2,6-Dioxo-3-piperidinyl)phthalimide
(+/-)-THALIDOMIDE
(-)-Thalidomide
(?)-Thalidomide
.alpha.-(N-Phthalimido)glutarimide
.alpha.-N-Phthalylglutaramide
.alpha.-Phthalimidoglutarimide
1,3-Dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline
14088-68-7
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-, (+-)-
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-, (R)-
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-, (S)-
2,6-Dioxo-3-phthalimidopiperidine
2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione
2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
2614-06-4
3-Phthalimidoglutarimide
5-22-13-00224 (Beilstein Handbook Reference)
50-35-1
731-40-8
841-67-8
AB00052362
AC-917
AC1L1KBZ
AC1Q6FJA
Actimid
AI3-50606
AIDS-000513
AIDS000513
Algosediv
alpha-(N-Phthalimido)glutarimide
alpha-N-Phthalylglutaramide
alpha-Phthalimidoglutarimide
Asidon 3
Asmadion
Asmaval
Bio1_000387
Bio1_000876
Bio1_001365
Bio2_000418
Bio2_000898
Bonbrain
Bonbrrin
BPBio1_000159
BRD-A93255169-001-06-9
BRN 0030233
BSPBio_000143
BSPBio_001156
BSPBio_003330
C07910
C13H10N2O4
Calmore
Calmorex
CC 4047
CCG-39878
CCRIS 8148
Celgene Brand of Thalidomide
CHEBI:105028
CHEBI:9513
CHEMBL468
cMAP_000022
Contergan
Corronarobetin
CPD000058524
D-Thalidomide
D00754
D013792
DB01041
Distaval
Distaxal
Distoval
DivK1c_000051
DRG-0184
E-217
Ectiluran
EINECS 200-031-1
ENMD 0995
Enterosediv
EU-0101224
Gastrinide
Glupan
Glutanon
Glutarimide, 2-phthalimido-
Grippex
Hippuzon
HMS1362J17
HMS1568H05
HMS1792J17
HMS1922E12
HMS1990J17
HMS2090O05
HMS2093G15
HMS2095H05
HMS2234C07
HMS3259C22
HMS3263F10
HMS500C13
HSDB 3586
I06-0197
IDI1_000051
IDI1_002173
Imida-Lab
Imidan (peyta)
Imidene
IN1061
Isomin
K 17
K-17
KBio1_000051
KBio2_000496
KBio2_002322
KBio2_003064
KBio2_004890
KBio2_005632
KBio2_007458
KBio3_000911
KBio3_000912
KBio3_002550
KBio3_002802
KBioGR_000496
KBioGR_001474
KBioGR_002322
KBioSS_000496
KBioSS_002324
Kedavon
Kevadon
L-Thalidomide
Lopac0_001224
LS-109463
LS-140
Lulamin
MLS000069353
N-(2,6-Dioxo-3-piperidyl)phthalimide
N-Phthalimidoglutamic acid imide
N-Phthaloylglutamimide
N-Phthalyl-glutaminsaeure-imid
N-Phthalyl-glutaminsaeure-imid [German]
N-Phthalylglutamic acid imide
NCGC00015989-03
NCGC00015989-04
NCGC00015989-05
NCGC00015989-06
NCGC00015989-07
NCGC00015989-08
NCGC00015989-09
NCGC00015989-10
NCGC00015989-11
NCGC00015989-12
NCGC00015989-13
NCGC00015989-14
NCGC00024708-02
NCGC00024708-03
NCGC00024708-04
NCGC00024708-05
NCGC00024708-06
NCGC00024708-07
NCGC00024708-08
NCGC00024708-09
NCGC00024708-10
NCGC00024708-11
NCI60_023904
NCIOpen2_003188
Neaufatin
Neo
Neosedyn
Neosydyn
Nerosedyn
Neufatin
Neurodyn
Neurosedin
Neurosedym
Neurosedyn
Nevrodyn
Nibrol
NINDS_000051
Noctosediv
Noxodyn
NSC 527179
NSC-66847
NSC527179
NSC66847
NSC91729
NSC91730
Pangul
Pantosediv
Phthalimide, N-(2,6-dioxo-3-piperidyl)-
phthalimide, n-(2,6-dioxo-3-piperidyl)-, ()-
Phthalimide, N-(2,6-dioxo-3-piperidyl)-, (+)-
Phthalimide, N-(2,6-dioxo-3-piperidyl)-, (+-)-
Phthalimide, N-(2,6-dioxo-3-piperidyl)-, (-)-
phthalimide, n-(2,6-dioxo-3-piperidyl)-, d-()-
Phthalimide, N-(2,6-dioxo-3-piperidyl)-, D-(+)-
Phthalimide, N-(2,6-dioxo-3-piperidyl)-, L-(-)-
Poly-Giron
Polygripan
Predni-Sediv
Prestwick0_000192
Prestwick1_000192
Prestwick2_000192
Prestwick3_000192
Prestwick_463
Pro-Bam M
Pro-ban M
Profarmil
Psycholiquid
Psychotablets
Quetimid
Quietoplex
R-(+)-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
S(-)-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
S1193_Selleck
SAM002564245
Sandormin
Sedalis
Sedalis sedi-lab
Sedimide
Sedin
Sedisperil
Sedoval
Shin-naito S
Shinnibrol
Sleepan
Slipro
SMR000058524
Softenil
Softenon
SPBio_000893
SPBio_002064
SPECTRUM1503607
Spectrum2_000707
Spectrum3_001715
Spectrum4_001087
Spectrum5_001791
ST51039042
Synovir
T144_SIGMA
T150_SIGMA
T151_SIGMA
Talargan
Talidomida
Talidomida [INN-Spanish]
Talidomide
Talidomide [DCIT]
Talimol
Talismol
Talizer
Telagan
Telargan
Telargean
Tensival
Thaled (TN)
Thalidomide
thalidomide ( and -)
Thalidomide (+ and -)
THALIDOMIDE (AIDS INITIATIVE)
Thalidomide (JAN/USP/INN)
Thalidomide (soluble form)
Thalidomide Celgene
Thalidomide Pharmion
Thalidomide [USAN:BAN:INN]
Thalidomide [USAN:INN:BAN]
Thalidomide-Supplied by Selleck Chemicals
Thalidomidum
Thalidomidum [INN-Latin]
Thalidomine USP26
Thalin
Thalinette
Thalomid
Thalomid (TM)
Thalomid (TN)
Thalomid, Thalidomide
Thalomide
Theophilcholine
Ulcerfen
UNII-4Z8R6ORS6L
UPCMLD-DP139
UPCMLD-DP139:001
Valgis
Valgraine
WLN: T56 BVNVJ C- DT6VMVTJ
WLN: T56 BVNVJ C- DT6VMVTJ -D
WLN: T56 BVNVJ C- DT6VMVTJ -L
Yodomin
ATC-Codes:
Side-Effects:
Side-EffectFrequency
somnolence0.28333333
endocrine disorders0.21700001
fever0.19466667
rash0.175
leukopenia0.16766667
headache0.14824998
dizziness0.14099999
diarrhea0.12775001
sweating0.1195
paresthesia0.108666666
asthenia0.09674999
agitation0.094
anemia0.088999994
lymphadenopathy0.088999994
chills0.08333333
malaise0.083
neuropathy0.083
vertigo0.083
rhinitis0.078
dry mouth0.078
insomnia0.0755
oral moniliasis0.072
acne0.071
sgot increased0.07
flatulence0.07
hematuria0.06999999
nausea0.06533333
dermatitis fungal0.063999996
pharyngitis0.06125
nervousness0.060999997
anorexia0.059666663
hyperlipemia0.059666663
infection0.058333337
pruritus0.057749998
pain0.057
albuminuria0.056999996
impotence0.0555
constipation0.05466667
abdominal pain0.053749997
sinusitis0.05325
edema peripheral0.051999997
back pain0.049000002
edema0.042
tooth pain0.042
neck rigidity0.042
tremor0.042
neck pain0.042
nail disorder0.0365
lymphedema0.0010
tachycardia0.0010
tumor0.0010
acute renal failure0.0010
petechiae0.0010
intestinal perforation0.0010
loss of consciousness0.0010
neutropenia0.0010
gynecomastia0.0010
nystagmus0.0010
seizures0.0010
purpura0.0010
hypocalcemia0.0010
hypercalcemia0.0010
syncope0.0010
aphthous stomatitis0.0010
hypokalemia0.0010
hyponatremia0.0010
stomach ulcer0.0010
lymphopenia0.0010
hyperkalemia0.0010
hypothyroidism0.0010
suicide attempt0.0010
metrorrhagia0.0010
sick sinus syndrome0.0010
pleural effusion0.0010
pancytopenia0.0010
myxedema0.0010
chronic myelogenous leukemia0.0010
diplopia0.0010
galactorrhea0.0010
enuresis0.0010
electrolyte imbalance0.0010
hypomagnesemia0.0010
grand mal convulsions0.0010
atrial fibrillation0.0010
amenorrhea0.0010
cardiac arrhythmias0.0010
migraine0.0010
dyspnea0.0010
dysesthesia0.0010
erythema multiforme0.0010
erythema nodosum0.0010
carpal tunnel0.0010
bradycardia0.0010
photosensitivity0
parotid gland enlargement0
psychosis0
pulmonary edema0
emphysema0
dry eyes0
pyuria0
retinitis0
sepsis0
psoriasis0
proteinuria0
pneumonia0
weakness0
allergic reaction0
dyspareunia0
pericarditis0
periodontitis0
bloating0
sarcoma0
cerebral ischemia0
hyperuricemia0
urinary frequency0
dementia0
elevated blood pressure0
phocomelia0
abnormal gait0
pneumocystis carinii pneumonia0
seborrhea0
thinking abnormal0
stupor0
thrombophlebitis0
tinnitus0
tooth disorder0
peripheral vascular disorder0
weight loss0
ulcer0
weight gain0
vomiting0
upper respiratory tract infection0
urticaria0
vaginal pruritus0
varicose vein0
venous thrombosis0
voice alteration0
thrombocytopenia0
microcytic anemia0
myalgia0
lightheadedness0
deep thrombophlebitis0
dry skin0
stevens - johnson syndrome0
eye pain0
bone pain0
muscle weakness0
lactic dehydrogenase increased0
stomatitis0
vaginal hemorrhage0
cerebrovascular accident0
emotional lability0
burning sensation0
sinus bradycardia0
viral infection0
eructation0
dehydration0
dysphagia0
decreased libido0
deafness0
cyst0
cystitis0
cough0
constitutional symptoms0
conjunctivitis0
confusion0
mental depression0
exfoliative dermatitis0
diabetes mellitus0
epistaxis0
toxic epidermal necrolysis0
eosinophilia0
endometriosis0
embolism0
eczema0
dysuria0
dyspepsia0
dysmenorrhea0
dyskinesia0
colitis0
cholangitis0
angioedema0
angina pectoris0
megaloblastic anemia0
macrocytic anemia0
hypochromic anemia0
aplastic anemia0
amyloidosis0
amnesia0
amblyopia0
alopecia0
anxiety0
apnea0
arthralgia0
cervical erosion0
cellulitis0
causalgia0
moniliasis0
bronchitis0
breast swelling0
skin benign neoplasm0
ataxia0
ascites0
arthritis0
agranulocytosis0
pancreatitis0
leukocytosis0
herpes simplex0
leukemia0
leg pain0
leg cramps0
lacrimation disorder0
arthrosis0
jaundice0
irritability0
influenza0
lung disorder0
lymphocytosis0
melasma0
palpitations0
pain in limb0
orchitis0
optic neuritis0
neuralgia0
myocardial infarction0
musculoskeletal pain0
muscle cramps0
menstrual flow0
meningitis0
siadh0
ichthyosis0
congestive heart failure0
heart failure0
cardiac arrest0
glossitis0
gastrointestinal hemorrhage0
gastroenteritis0
gallbladder disease0
flushing0
fatigue0
euphoria0
hemoptysis0
hepatitis0
hepatomegaly0
hypotension0
hypoglycemia0
hypertension0
hypernatremia0
hyperglycemia0
hyperesthesia0
hypercholesterolemia0
bilirubinemia0
hirsutism0
hernia0
esophagitis0

Target

show target details
Uniprot ID:CP2CJ_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC17
CYPIIC19
Cytochrome P450 2C19
Mephenytoin 4-hydroxylase
P450-11A
P450-254C
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: