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Drug-Target Interaction

Drug

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PubChem ID:5408
Structure:
Synonyms:
.delta.(4)-Androsten-17.beta.-ol-3-one
.delta.(sup4)-Androsten-17(.beta.)-ol-3-one
.delta.(Sup4)-Androsten-17.beta.-ol-3-one
.DELTA.4-Androsten-17.beta.-ol-3-one
10.alpha.-Androst-4-en-3-one, 17.beta.-hydroxy-
14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5
17-Hydroxy-(17.beta.)-androst-4-en-3-one
17-hydroxyandrost-4-en-3-one
17.beta.-Hydroxy-.delta.(sup4)-androsten-3-one
17.beta.-Hydroxy-4-androsten-3-one
17.beta.-Hydroxyandrost-4-en-3-one
571-41-5
58-22-0
9-BETA-10-ALPHA-TESTOSTERONE
9.beta.,10.alpha.-Testosterone
AC1L1KAH
AC1Q2QEH
AC1Q6OGE
AKOS000490915
Androlin
Andronaq
Androst-4-en-17.beta.-ol-3-one
Androst-4-en-3-one, 17-hydroxy-, (10.alpha.,17.beta.)-
Androst-4-en-3-one, 17-hydroxy-, (17.alpha.)-
Androst-4-en-3-one, 17-hydroxy-, (17.beta.)-
Androst-4-en-3-one, 17.alpha.-hydroxy-
Androst-4-en-3-one, 17.beta.-hydroxy-
Andrusol
AR-1C1126
ARONIS001136
component of Di-Genik
component of Di-Met
component of Duogen
component of Mal-O-Fem
CPD000109709
Cristerona T
EU-0070267
F0452-4293
Geno-cristaux Gremy
HMS2268M04
HMS3259H09
Homosteron
Homosterone
I06-0173
Malerone
Malogen, aquaspension injection
Mertestate
MLS000113817
MolPort-000-691-652
Neo-Hombreol F
Neotestis
NSC523833
NSC9700
Oprea1_852285
Oreton
Oreton F
Orquisteron
Perandren
Percutacrine androgenique
Primotest
Primoteston
SAM002548950
SMR000109709
STK013235
Sustanon
Sustanone
Synandrol F
Teslen
Testandrone
Testiculosterone
Testobase
Testopropon
Testosteroid
Testosteron
TESTOSTERONE
Testostosterone
Testoviron
Testoviron Schering
Testoviron T
Testrone
Testryl
trans-Testosterone
Virormone
Virosterone
WLN: L E5 B666 OV MUTJ A1 E1 FQ
Side-Effects:
Side-EffectFrequency
pruritus0.08135714
lab test abnormal0.047799997
contact dermatitis0.04
gum pain0.031
blister0.028461538
anemia0.025
acne0.022789473
skin dry0.019
erythema0.01692308
peripheral edema0.015000001
headache0.01395652
asthenia0.013333333
nervousness0.013333333
gynecomastia0.0066999993
blood pressure increased0.0066666664
mastodynia0.0064285705
decreased libido0.005933334
gastrointestinal bleeding0.0057500005
rash0.005384616
benign prostatic hyperplasia0.0050
flushes0.0050
hypertension0.004999999
edema0.002727273
prostate carcinoma0.0023750002
insomnia0.0021428573
alopecia0.0016956517
seborrhea0.0010
priapism0.0010
serum sickness0.0010
peliosis0.0010
sleep apnea0.0010
incontinence0.0010
urticaria0.0010
myalgia0.0010
glucose tolerance impaired0.0010
testicular atrophy0.0010
allergic reaction0.0010
abnormal liver function tests0.0010
weight increase0.0010
malaise0.0010
vomiting0.0010
vascular disorders0.0010
polycythemia0.0010
abdominal pain0.0010
dysuria0.0010
dyspnea0.0010
dizziness0.0010
diarrhea0.0010
dermatitis0.0010
connective tissue disorders0.0010
confusion0.0010
carcinoma0.0010
breast disorder0.0010
arthralgia0.0010
anxiety0.0010
endocrine disorders0.0010
epididymitis0.0010
fatigue0.0010
personality disorder0.0010
nausea0.0010
mediastinal disorders0.0010
hepatic neoplasms0.0010
renal disorders0.0010
impotence0.0010
hypersensitivity reaction0.0010
elevated cholesterol0.0010
hirsuitism0.0010
hepatoma0.0010
bleeding0.0010
hematuria0.0010
polyps0
migraine0
infection0
amnesia0
hypertriglyceridemia0
pelvic pain0
sweating0
heart disease0
scarring0
urinary hesitancy0
skin irritation0
ulcer0
stomatitis0
amenorrhea0
toothache0
habituation0
irritability0
emotional lability0
cognitive dysfunction0
depressed mood0
deep thrombophlebitis0
cyst0
peripheral vascular disorder0
angina pectoris0
cerebral hemorrhage0
renal failure0
adenomas0
anger0
paresthesia0
clotting0
leukoplakia0
leukopenia0
deep vein thrombosis0
hypokalemia0
varicocele0
pain0
urinary retention0
urinary urgency0
memory loss0
masculinization0
dry mouth0
urinary tract infection0
gingivitis0
pneumonia0
jaundice0
coronary artery disease0
hyperlipidemia0
breast enlargement0
abdominal cramps0
seizures0
vertigo0
asthma0
nocturia0
prostatic specific antigen increase0
penile pain0
chills0
apnea0

Target

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Uniprot ID:SHBG_HUMAN
Synonyms:
ABP
SBP
Sex hormone-binding globulin
Sex steroid-binding protein
SHBG
TeBG
Testis-specific androgen-binding protein
Testosterone-estradiol-binding globulin
Testosterone-estrogen-binding globulin
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:1D2S 1F5F 1KDK 1KDM 1LHN 1LHO 1LHU 1LHV 1LHW
Structure:
1LHW

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: