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Drug-Target Interaction

Drug

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PubChem ID:5381
Structure:
Synonyms:
118292-40-3
3-Pyridinecarboxylic acid,
3-Pyridinecarboxylic acid, 6-((3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl)-, ethyl ester
3-Pyridinecarboxylic acid, 6-((3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl)-,ethyl ester
AGN 190168
AGN-190168
Avage
Avage (TN)
C086827
C12531
C21H21NO2S
CHEBI:32184
D01132
DB00799
Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate
ethyl 6-(2-(4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate
ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-6-yl)ethynyl]nicotinate
ethyl 6-[2-(4,4-dimethylthiochroman-6-yl)ethynyl]pyridine-3-carboxylate
LS-130838
NCGC00167525-01
Suretin
TAZAROTENE
Tazarotene (JAN/USAN/INN)
Tazarotene [USAN:INN]
Tazorac
Tazoral
ZINC01542199
Zorac
ATC-Codes:
Side-Effects:
Side-EffectFrequency
erythema0.34
burning sensation0.26
dry skin0.16
pruritus0.1
irritation skin0.1
contact dermatitis0.08
acne0.03
rash0.03
dermatitis0
edema0
hyperpigmentation0
hypertriglyceridemia0
hemorrhage0
facial pain0
peripheral edema0

Target

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Uniprot ID:RARA_HUMAN
Synonyms:
Nuclear receptor subfamily 1 group B member 1
RAR-alpha
Retinoic acid receptor alpha
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:1DKF 1DSZ
Structure:
1DSZ

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----
----
---63

References: