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Drug-Target Interaction

Drug

show drug details
PubChem ID:5379
Structure:
Synonyms:
(+-)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-
1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
112811-59-3
160738-57-8
180200-66-2 (SESQUIHYDRATE)
3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-
AIDS-044913
AIDS-104746
AIDS044913
AIDS104746
AM 1155
AM-1155
AM-1155 (*Sesquihydrate*)
BB_SC-1123
BMS 206584-01
BMS-206584
Bonoq
BSPBio_002697
C07661
CG 5501
CG-5501
CHEBI:5280
CPD000043336
DB01044
Gaity
Gatiflo
Gatifloxacin
Gatifloxacin & Gamma Interferon
Gatifloxacin [USAN:INN]
Gatilox
Gatiquin
Gatispan
GTFX
KBio2_002442
KBio2_005010
KBio2_007578
KBio3_001917
KBioGR_001613
KBioSS_002448
LS-184402
MLS000040259
MLS000759493
NCGC00095126-01
NCGC00095126-02
NCGC00178525-01
PD 135432
PD-135432
PD135432
Quinolone der.
SAM001246715
SMR000043336
SPBio_000353
SPECTRUM1504272
Spectrum2_000487
Spectrum3_000999
Spectrum4_001127
Spectrum5_001468
Spectrum_001909
Tequin
TL8001438
Zymar
ATC-Codes:
Side-Effects:
Side-EffectFrequency
hepatitis0.0010
hyperglycemia0.0010
coma0.0010
tinnitus0.0010
conjunctivitis0.0010
thrombocytopenia0.0010
corneal disorder0.0010
corneal ulcer0.0010
dacryocystitis0.0010
tremor0.0010
infection0.0010
stevens - johnson syndrome0.0010
headache0.0010
eye redness0.0010
pruritis0.0010
hypoglycemia0.0010
anaphylactic reaction0.0010
angioneurotic edema0.0010
uveitis0.0010
pancreatitis0.0010
parasthesia0.0010
acute renal failure0.0010
keratoconjunctivitis0.0010
allergic reaction0.0010
edema0.0010
blepharitis0.0010
hypotension0.0010
syncope0.0010
tachycardia0
chest pain substernal0
sweating0
stomatitis0
seizures0
neutropenia0
psychosis0
sneezing0
ptosis0
pharyngitis0
palpitations0
erythema0
urticaria0
sore throat0
rectal hemorrhage0
dry eyes0
blurred vision0
photosensitivity0
bradycardia0
lymphadenopathy0
insomnia0
pseudomembranous colitis0
rhinorrhea0
paranoia0
thinking abnormal0
myalgia0
dry skin0
abnormal vision0
vomiting0
chills0
agitation0
photophobia0
peripheral edema0
panic attacks0
mouth ulceration0
migraine0
bone pain0
eye pain0
vertigo0
nervousness0
abdominal pain0
confusion0
constipation0
cyst0
dysphagia0
depersonalization0
dermatitis0
diabetes mellitus0
dizziness0
somnolence0
dyspepsia0
colitis0
chest pain0
neck pain0
anorexia0
anxiety0
arthralgia0
arthritis0
asthenia0
asthma0
ataxia0
back pain0
bronchospasm0
oral moniliasis0
dyspnea0
dysuria0
hematemesis0
hematuria0
hemorrhage0
hyperesthesia0
hypertension0
iritis0
keratitis0
leg cramps0
breast pain0
metrorrhagia0
hallucinations0
halitosis0
glossitis0
ear pain0
ecchymosis0
epistaxis0
euphoria0
rash0
fever0
flatulence0
gastritis0
gastrointestinal hemorrhage0
gingivitis0
nausea0

Target

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Uniprot ID:GYRB_ECOLI
Synonyms:
DNA gyrase subunit B
EC-Numbers:5.99.1.3
Organism:Escherichia coli
strain K12
PDB IDs:1AJ6 1EI1 1KZN
Structure:
1KZN

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: