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Drug-Target Interaction

Drug

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PubChem ID:5353980
Structure:
Synonyms:
(3E)-6-oxo-3-[[4-(pyridin-2-ylsulfamoyl)phenyl]hydrazinylidene]cyclohexa-1
(3E)-6-oxo-3-[[4-(pyridin-2-ylsulfamoyl)phenyl]hydrazinylidene]cyclohexa-1,4-diene-1-carboxylic acid
2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid
4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene
5-((p-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid
5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid
5-(p-(2-Pyridylsulfamyl)phenylazo)salicylic acid
5-22-08-00433 (Beilstein Handbook Reference)
5-[4-(2-Pyridylsulfamoyl)-phenylazo]-salicylic acid
5-[[p-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid
599-79-1
AC-20497
AC1NS4RK
Accucol
AIDS-059756
AIDS059756
AKOS002311709
Asulfidine
Azopyrin
Azopyrine
Azosulfidin
Azulfidine
Azulfidine EN
Benzoic acid, 2-hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)-
Benzoic acid, 2-Hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]azo]-
Benzosulfa
BPBio1_000527
BRN 0356241
BSPBio_000479
BSPBio_002888
CCG-100987
CCG-39145
CCRIS 4713
CHEBI:45504
CHEMBL421
cMAP_000018
Colo-Pleon
CPD000059146
DB00795
DB08518
DivK1c_000860
EINECS 209-974-3
HMS1921C05
HMS2051J21
HMS2090P13
HMS2092K07
HMS2096H21
HMS2232H07
HMS502K22
HSDB 3395
IDI1_000860
KBio1_000860
KBio2_001478
KBio2_002314
KBio2_004046
KBio2_004882
KBio2_006614
KBio2_007450
KBio3_002108
KBio3_002794
KBioGR_000753
KBioGR_002314
KBioSS_001478
KBioSS_002316
MLS000759399
MLS001424109
MolPort-001-792-507
NINDS_000860
NSC 203730
NSC 667219
NSC203730
NSC667219
Prestwick0_000520
Prestwick1_000520
Prestwick2_000520
Prestwick3_000520
Reupirin
Rorasul
S.A.S. 500
S.A.S.-500
Salazo-sulfapyridinum
Salazopiridazin
Salazopyridin
Salazopyrin
Salazopyrine
Salazosulfapiridina [INN-Spanish]
Salazosulfapyridin
Salazosulfapyridine
Salazosulfapyridinum [INN-Latin]
Salicylazosulfapyridine
Salicylic acid, 5-((p-(2-pyridylsulfamoyl)phenyl)azo)-
Salisulf
SAM001246530
Sas-500
SASP
SI-88
SMP2_000059
SMR000059146
SPBio_001032
SPBio_002400
SPECTRUM1500552
Spectrum2_001216
Spectrum3_001364
Spectrum4_000347
Spectrum5_001443
Spectrum_000998
ST50767935
Sulcolon
Sulfasalazin
Sulfasalazina [INN-Spanish]
SULFASALAZINE
Sulfasalazine [USAN:INN]
Sulfasalazinum [INN-Latin]
Sulphasalazine
TL8003811
W-T Sasp Oral
ATC-Codes:
Side-Effects:
Side-EffectFrequency
cirrhosis0.0010
elevated liver function tests0.0010
liver necrosis0.0010
jaundice0.0010
liver failure0.0010
pericarditis0
peripheral neuropathy0
pleurisy0
myelodysplastic syndrome0
pneumonia0
proteinuria0
pruritus0
polyarteritis nodosa0
parapsoriasis0
pancytopenia0
pancreatitis0
neutropenia0
nephrotic syndrome0
nephrosis0
interstitial nephritis0
myocarditis0
purpura0
rhabdomyolysis0
pseudomembranous colitis0
insomnia0
liver function tests abnormal0
fibrosing alveolitis0
macrocytosis0
encephalopathy0
vertigo0
vasculitis0
urticaria0
urinary tract infection0
erythema0
tinnitus0
thrombocytopenia0
stomatitis0
stevens - johnson syndrome0
serum sickness0
rheumatism0
hearing loss0
transverse myelitis0
methemoglobinemia0
somnolence0
dizziness0
diarrhea0
exfoliative dermatitis0
mental depression0
cough0
convulsions0
cancer0
ataxia0
arthralgia0
anorexia0
hemolytic anemia0
aplastic anemia0
anemia0
anaphylaxis0
alopecia0
agranulocytosis0
dyspepsia0
dyspnea0
edema0
aseptic meningitis0
meningitis0
lupus0
leukopenia0
hypoglycemia0
hypersensitivity0
hepatitis0
hematuria0
headache0
hallucinations0
goiter0
fever0
rash0
erythema multiforme0
toxic epidermal necrolysis0
eosinophilia0
enterocolitis0
abdominal pain0

Target

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Uniprot ID:LOX5_HUMAN
Synonyms:
5-lipoxygenase
5-LO
Arachidonate 5-lipoxygenase
EC-Numbers:1.13.11.34
Organism:Homo sapiens
Human
PDB IDs:2ABV
Structure:
2ABV

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: