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Drug-Target Interaction

Drug

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PubChem ID:5344
Structure:
Synonyms:
127-69-5
207522-06-3
2200-44-4
2200-44-4 (mono-hydrochloride salt)
3,4-Dimethyl-5-sulfanilamidoisoxazole
3,4-Dimethyl-5-sulfonamidoisoxazole
3,4-Dimethyl-5-sulphanilamidoisoxazole
3,4-Dimethyl-5-sulphonamidoisoxazole
3,4-dimethylisoaxazole-5-sulfanilimide
3,4-Dimethylisoxale-5-sulfanilamide
3,4-Dimethylisoxazole-5-sulfanilamide
3,4-Dimethylisoxazole-5-sulphanilamide
4-27-00-04747 (Beilstein Handbook Reference)
4-amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide
4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide
4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulphonamide
4-Amino-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide
4-amino-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide
4299-60-9 (DIOLAMINE)
5-(4-aminop henylsulfonamido)-3,4-dimethylisoxazole
5-(4-Aminophenylsulfonamido)-3,4-dimethylisoxazole
5-(p-Aminobenzenesulfonamido)-3,4-dimethylisooxale
5-(p-Aminobenzenesulfonamido)-3,4-dimethylisoxazole
5-(p-Aminobenzenesulphonamido)-3,4-dimethylisoxazole
5-Sulfanilamido-3,4-dimethyl-isoxazole
5-Sulfanilamido-3,4-dimethylisoxazole
5-Sulphanilamido-3,4-dimethyl-isoxazole
6155-81-3
6155-81-3 (mono-lithium salt)
AB00052104
AC-1941
AC1L1K55
Accuzole
AI3-24003
AIDS-008207
AIDS008207
AKOS000119074
AKOS000310021
Alphazole
Amidoxal
Astrazolo
Azo Gantrisin
Azosulfizin
Bactesulf
Barazae
BAS 00531889
Benzenesulfonamide, 4-amino-N-(3,4-dimethyl-5-isoxazolyl)-
BIDD:GT0322
Bio-0765
BPBio1_000405
BRD-K50859149-001-05-4
BRN 0263871
BSPBio_000367
BSPBio_003376
C07318
C11H13N3O3S
CAS-127-69-5
CCG-39263
CCRIS 568
CHEBI:102484
CHEMBL453
Chemouag
component of Azo Gantrisin
Component of Azo Gantrisin Accuzole
component of Azo-Sulfizin
Cosoxazole
CPD000037657
D00450
DB00263
DivK1c_000579
Dorsulfan
Dorsulfan Warthausen
EINECS 204-858-9
Entusil
Entusul
ERYZOLE
G-sox
Ganda
Gantrisin
Gantrisin (TN)
Gantrisine
Gantrisona
Gantrosan
HMS1569C09
HMS2092K13
HMS2096C09
HMS2233G23
HMS3259C06
HMS501M21
HSDB 797
IDI1_000579
Isoxamin
J-Sul
KBio1_000579
KBio2_001504
KBio2_004072
KBio2_006640
KBio3_002596
KBioGR_000757
KBioSS_001504
Koro-sulf
LS-713
Mixture Name
MLS000028495
MLS000037737
MLS000563718
N'-(3,4)Dimethylisoxazol-5-yl-sulphanilamide
N(1)-(3,4-dimethyl-5-isoxazolyl)sulfanilamide
N(1)-(3,4-dimethyl-5-isoxazolyl)sulphanilamide
N(sup 1)-(3,4-dimethyl-5-isoxazolyl)-sulfanilamide
N(sup 1)-(3,4-Dimethyl-5-isoxazolyl)sulfanilamide
N(sup 1)-(3,4-Dimethyl-5-isoxazolyl)sulphanilamide
N(sup1)-(3,4-Dimethyl-5-isoxazolyl)sulfanilamide
N1-(3,4-Dimethyl-5-isoxazolyl)sulfanilamide
NCGC00016384-01
NCGC00016384-02
NCGC00016384-03
NCGC00016384-04
NCGC00016384-05
NCGC00016384-06
NCGC00016384-07
NCGC00016384-08
NCGC00016384-09
NCGC00016384-10
NCGC00016384-11
NCGC00016384-12
NCGC00023116-02
NCGC00023116-05
NCGC00023116-06
NCGC00023116-07
NCGC00023116-08
NCI-C50022
Neazolin
Neoxazoi
Neoxazol
NINDS_000579
Norilgan-S
Novazolo
Novosaxazole
NSC 13120
NSC 683536
NSC13120
NSC33807
NSC38588
NSC683536
NU 445
Oprea1_680668
Oprea1_828173
Pancid
Prestwick0_000334
Prestwick1_000334
Prestwick2_000334
Prestwick3_000334
Prestwick_726
Renosulfan
Resoxol
Roxosul
Roxosul tablets
Roxoxol
S1916_Selleck
S6377_SIGMA
SAM002554929
Saxosozine
SBB007602
SI
SK-Soxazole
SMR000037657
Sodizole
Solfafurazolo
Solfafurazolo [DCIT]
Sosol
Soxamide
SOXAZOLE
Soxisol
Soxitabs
SOXO
Soxomide
SPBio_001449
SPBio_002288
SPECTRUM1500555
Spectrum2_001325
Spectrum3_001728
Spectrum4_000349
Spectrum5_001222
Spectrum_001024
ST059445
Stansin
STK400452
Sulbio
Sulfadimethylisoxazole
Sulfadimethyloxazole
Sulfafuraz ole
Sulfafurazol
Sulfafurazole
Sulfafurazole (INN)
Sulfafurazole, Gantrisin Pediatric, Sulfisoxazole
Sulfafurazolum
Sulfafurazolum [INN-Latin]
Sulfagan
Sulfagen
Sulfaisoxazole
Sulfalar
Sulfanilamide, N(sup 1)-(3,4-dimethyl-5-isoxazolyl)-
Sulfanilamide, N(sup1)-(3,4-dimethyl-5-isoxazolyl)-
Sulfanilamide, N1-(3,4-dimethyl-5-isoxazolyl)-
Sulfapolar
Sulfasol
Sulfasoxazole
Sulfasoxizole
Sulfazin
Sulfazin (VAN)
Sulfisin
Sulfisonazole
Sulfisoxasole
Sulfisoxazol
Sulfisoxazole
Sulfisoxazole (JP15/USP)
Sulfisoxazole (JP16/USP)
Sulfisoxazole - Carc
Sulfisoxazole dialamine
Sulfisoxazole diolamine
Sulfisoxazole [USAN]
Sulfisoxazole-Supplied by Selleck Chemicals
Sulfisoxazolum
Sulfizin
Sulfizol
Sulfizole
Sulfofurazole
Sulfoxol
Suloxsol
Sulphadimethylisoxazole
Sulphafuraz
Sulphafurazol
Sulphafurazole
Sulphafurazolum
Sulphaisoxazole
Sulphisoxazol
Sulphisoxazole
Sulphofurazole
Sulsoxin
Thiasin
TL-Azole
Tocris-0731
U.S.-67
UNII-740T4C525W
Unisulf
UPCMLD00X127-69-5:001
Urisoxin
Uritrisin
Urogan
US-67
V-Sul
Vagilia
WLN: T5NOJ CMSWR DZ& D1 E1
[(4-aminophenyl)sulfonyl](3,4-dimethylisoxazol-5-yl)amine
ATC-Codes:
Side-Effects:
Side-EffectFrequency
allergic reaction0
purpura0
psychosis0
pruritus0
pneumonia0
polyarteritis nodosa0
paresthesia0
weakness0
pancreatitis0
palpitations0
neuritis0
nephrosis0
nausea0
myocarditis0
methemoglobinemia0
melena0
lupus0
leukopenia0
serum sickness0
stevens - johnson syndrome0
stomatitis0
hearing loss0
pseudomembranous colitis0
insomnia0
shortness of breath0
photosensitivity0
myalgia0
apathy0
chills0
urinary retention0
vomiting0
vertigo0
vasculitis0
urticaria0
tinnitus0
thrombocytopenia0
tachycardia0
syncope0
acute renal failure0
jaundice0
dizziness0
diarrhea0
exfoliative dermatitis0
cough0
convulsions0
clotting0
ataxia0
asthenia0
arthralgia0
arteritis0
anxiety0
anorexia0
angioedema0
aplastic anemia0
anemia0
anaphylaxis0
agranulocytosis0
somnolence0
edema0
eosinophilia0
hypoglycemia0
salivary gland enlargement0
hypertension0
hepatitis0
hematuria0
headache0
hallucinations0
goiter0
glossitis0
gastrointestinal hemorrhage0
flushing0
flatulence0
fever0
fatigue0
rash0
erythema multiforme0
toxic epidermal necrolysis0
abdominal pain0

Target

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Uniprot ID:CP2C8_HUMAN
Synonyms:
CYPIIC8
Cytochrome P450 2C8
P450 form 1
P450 IIC2
P450 MP-12/MP-20
S-mephenytoin 4-hydroxylase
EC-Numbers:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:1PQ2 2NNH 2NNI 2NNJ 2VN0
Structure:
2VN0

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: