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Drug-Target Interaction

Drug

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PubChem ID:5311297
Structure:
Synonyms:
2-[2-[(3R)-3-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-sulfanylpr
AC1NSKDT
CID5311297
Montelukast
Side-Effects:
Side-EffectFrequency
epistaxis0.0010
erythema nodosum0.0010
tremor0.0010
connective tissue disorders0.0010
swelling0.0010
mediastinal disorders0.0010
liver disease0.0010
breast tenderness0.0010
cardiac disorders0.0010
anxiousness0.0010
hepatitis0.0009
rash0.00087
hypersensitivity0.00087
eosinophilia0.00086
insomnia0.00086
nausea0.00086
muscle cramps0.00086
edema0.00086
pancreatitis0.00086
pruritus0.00086
anaphylaxis0.00086
angioedema0.00086
neuropathy0.00086
myalgia0.00086
vomiting0.00086
restlessness0.00086
vasculitis0.00086
urticaria0.00086
bleeding tendency0.00086
diarrhea0.00086
seizures0.00086
hallucinations0.00085
palpitations0.00084
arthralgia0.00084
asthma0.00084
paraesthesia0.00081
drowsiness0.00077
dyspepsia0.00077
fever0.00033
abdominal pain0.00033
pain0.00033
fatigue0.00033
asthenia0.00033
upper respiratory tract infection0
dermatitis0
decreased libido0
conjunctivitis0
viral infection0
benign prostatic hyperplasia0
wheezing0
rhinorrhea0
acute bronchitis0
sgot increased0
influenza0
atopic dermatitis0
sinusitis0
irritability0
laryngitis0
infection0
gastroenteritis0
myopia0
otitis0
otitis media0
eczema0
pharyngitis0
pneumonia0
ear pain0
pyuria0
varicella0
sinus headache0
tonsillitis0

Target

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Uniprot ID:LOX5_HUMAN
Synonyms:
5-lipoxygenase
5-LO
Arachidonate 5-lipoxygenase
EC-Numbers:1.13.11.34
Organism:Homo sapiens
Human
PDB IDs:2ABV
Structure:
2ABV

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: