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Drug-Target Interaction

Drug

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PubChem ID:5311181
Structure:
Synonyms:
(5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-y
78919-13-8
AC1NSK5T
CHEMBL494
Ciloprost
D02721
E-1030
Endoprost
HMS2090A19
Ilom dine
Ilomedin
Ilomedine
Iloprost
Iloprost (INN)
Iloprost (USAN/INN)
SH-401
Ventavis
Ventavis (TN)
ZK-36374
[3H]-Iloprost
ATC-Codes:
Side-Effects:
Side-EffectFrequency
flushing0.18
cough0.13
headache0.1
insomnia0.06
alk phos increased0.05
vomiting0.05
nausea0.05
hypotension0.05
back pain0.04
tongue pain0.04
flu syndrome0.04
syncope0.03
pneumonia0.03
palpitations0.03
muscle cramps0.03
hemoptysis0.03
dizziness0.0010
bronchospasm0.0010
wheezing0.0010
gingival bleeding0.0010
diarrhea0.0010
epistaxis0.0010
renal failure0
dyspnea0
supraventricular tachycardia0
chest pain0
congestive heart failure0
peripheral edema0

Target

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Uniprot ID:PI2R_HUMAN
Synonyms:
PGI receptor
Prostacyclin receptor
Prostaglandin I2 receptor
Prostanoid IP receptor
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----
--27-
6.5---

References: