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Drug-Target Interaction

Drug

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PubChem ID:5282481
Structure:
Synonyms:
(E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine
(E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine hydrochloride
1-Naphthalenemethanamine, N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-, (E)-, monohydrochloride
1-Naphthalenemethanamine, N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-, (E)-,monohydrochloride
78628-80-5
Afogan
Ambap2235
C21H25N.HCl
CPD000469152
D02219
Daskil
DRG-0286
InnoNyx
Lamisil
Lamisil (TN)
Lamisil AT
Lamisil Krem
LS-94723
MLS001066620
MLS001304037
MLS001401424
NM-100060
SAM001246565
SF 86-327 hydrochloride
SF-86327
SMR000469152
TerbiFoam
Terbinafina [Spanish]
TERBINAFINE HCl
Terbinafine hydrochloride
Terbinafine hydrochloride (JAN)
Terbinafinum [Latin]
Terbisil
Side-Effects:
Side-EffectFrequency
dizziness0.0010
liver failure0.0010
weight loss0.0010
vomiting0.0010
fatigue0.0010
allergic reactions0.0010
paraesthesia0.0010
thrombocytopenia0.0010
visual field defects0.0010
rhabdomyolysis0.0010
systemic lupus erythematosus0.0010
psoriasis0.0010
neutropenia0.0010
malaise0.0010
myalgia0.0010
acute pancreatitis0.0010
agranulocytosis0.0010
hair loss0.0010
anaphylaxis0.0010
anemia0.0010
angioedema0.0010
arthralgia0.0010
pancytopenia0.0010
headache0
hyperpigmentation0
pruritus0
abdominal pain upper0
thrombotic thrombocytopenic purpura0
retinopathy0
dry mouth0
elevated liver enzymes0
photosensitivity0
stevens - johnson syndrome0
rhinorrhea0
toothache0
erythema0
urticaria0
upper respiratory tract infection0
pain0
erythema multiforme0
toxic epidermal necrolysis0
eczema0
dyspepsia0
abdominal pain0
diarrhea0
contact dermatitis0
cough0
confusion0
arthritis0
rash0
fever0
flatulence0
nausea0
nasopharyngitis0
nasal congestion0
muscle cramps0
liver disease0
jaundice0
influenza0
hypoglycemia0
blood dyscrasia0
gastritis0
anorexia0

Target

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Uniprot ID:CP2C9_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC9
Cytochrome P450 2C9
P-450MP
P450 MP-4/MP-8
P450 PB-1
S-mephenytoin 4-hydroxylase
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:1OG2 1OG5 1R9O
Structure:
1R9O

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: