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Drug-Target Interaction

Drug

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PubChem ID:5281670
Structure:
Synonyms:
()-oxazepam hemisuccinate sodium salt
11128-85-1
2',3,4',5,7-Pentahydroxyflavone
2',4',3,5,7-Pentahydroxyflavone
2',4',5,7-Tetrahydroxyflavan-3-ol
2'-Hydroxypelargidenolon 1522
2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one
2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one
3,5 7 2 4-Pentahydroxyflavone
3,5,7,2',4'-Pentahydroxyflavone
3,5,7,2',4'-Pentahydroxyflavonol
480-16-0
4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-
4H-1-Benzopyran-4-one, 2-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-
5-18-05-00492 (Beilstein Handbook Reference)
69870_FLUKA
91A9D69E-FAB0-45CD-90E5-DEEFBADE86C1
AC1NQYUY
ACon1_000260
AI3-38057
AIDS-001407
AIDS001407
AKOS001582671
Al-Morin
Aurantica
BIDD:ER0115
Bio-0589
Bois d'Arc
Bois d'arc [French]
Bois d,Arc
BRN 0327474
BSPBio_003541
C.I. 75660
C.I. Natural Yellow 11
C.I. Natural Yellow 11 (VAN)
C.I. Natural Yellow 8
C.I.Natural Yellow 8
C008548
C10105
C15H10O7
Calico Yellow
CCG-39036
CCRIS 8680
CHEMBL28626
DivK1c_000958
EINECS 207-542-9
EU-0100776
Flavone, 2',3,4',5,7-pentahydroxy-
HMS1921P12
HMS3262K14
HMS502P20
IDI1_000958
KBio1_000958
KBio2_001714
KBio2_004282
KBio2_006850
KBio3_002824
KBioGR_002268
KBioSS_001714
LMPK12112517
Lopac-M-4008
Lopac0_000776
LS-69029
M 4008
M-8200
MEGxp0_001864
MLS000069618
MolPort-001-742-584
Morin
Morin hydrate
MORIN, REAG
NCGC00015672-01
NCGC00015672-02
NCGC00015672-05
NCGC00015672-14
NCGC00022214-03
NCGC00022214-04
NCGC00022214-05
NCGC00022214-06
NCGC00022214-07
NCGC00178000-01
NCGC00178000-02
NCI60_001647
NINDS_000958
NSC 19801
NSC-19801
NSC19801
Osage Orange
Osage Orange Crystals
Osage Orange Extract
P0041
SBB008853
SDCCGMLS-0003296.P003
SMP1_000199
SMR000058259
SPBio_000929
SPECTRUM1502259
Spectrum2_000715
Spectrum3_001941
Spectrum4_001924
Spectrum5_000737
Spectrum_001234
Toxylon Pomiferum
ZINC03881558
Zlut prirodni 11
Zlut prirodni 11 [Czech]

Target

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Uniprot ID:PIM1_HUMAN
Synonyms:
Proto-oncogene serine/threonine-protein kinase Pim-1
EC-Numbers:2.7.11.1
Organism:Homo sapiens
Human
PDB IDs:1XQZ 1XR1 1XWS 1YHS 1YI3 1YI4 1YWV 1YXS 1YXT 1YXU 1YXV 1YXX 2BIK 2BIL 2BZH 2BZI 2BZJ 2BZK 2C3I 2J2I 2O3P 2O63 2O64 2O65 2OBJ 2OI4 3BGP 3BGQ 3BGZ 3BWF 3C4E 3CXW 3CY2 3CY3 3DCV 3F2A
Structure:
3F2A

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--2700-

References: