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Drug-Target Interaction

Drug

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PubChem ID:5281037
Structure:
Synonyms:
(4-carboxybenzyl)imidazole-5-acrylic acid
(E)-2-Butyl-1-(p-carboxybenzyl)-alpha-2-thenylimidazole-5-acrylic acid
(E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid
(E)-alpha{[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazole-5-yl]methylene}-2-thiopheneproprionic acid
133040-01-4
2-Thiophenepropanoic acid, alpha-((2-butyl-1-((4-carboxyphenyl)methyl)-lH-imidazol-5-yl)methylene)-, (E)-
4-({2-butyl-5-[(1E)-2-carboxy-3-(2-thienyl)prop-1-en-1-yl]-1H-imidazol-1-y
4-({2-butyl-5-[(1E)-2-carboxy-3-(2-thienyl)prop-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid
C07467
C23H24N2O4S
CHEBI:4814
D04040
Eprosartan
Eprosartan (USAN/INN)
Eprosartan [USAN:BAN:INN]
LS-172855
NCGC00164557-01
SK&F 108566
SK&F-108566
SKF-108566
STOCK6S-51357
Teveten
TL8000785
ATC-Codes:
Side-Effects:
Side-EffectFrequency
upper respiratory tract infection0.07
coughing0.036666665
pharyngitis0.036666665
rhinitis0.036666665
abdominal pain0.016666666
fatigue0.016666666
infection viral0.016666666
arthralgia0.016666666
hypertriglyceridemia0.0066666664
urinary tract infection0.0066666664
renal failure0.0010
dizziness0.0010
swelling0.0010
postural hypotension0.0010
urticaria0.0010
hypotension0.0010
rash0.0010
myositis0.0010
pruritus0.0010
headaches0.0010
cardiac insufficiency0.0010
rhabdomyolysis0.0010
muscle pain0.0010
angioedema0.0010
asthenia0.0010
muscle weakness0.0010
otitis externa0
bradycardia0
purpura0
ecg abnormal0
urinary frequency0
nervousness0
periodontitis0
increased sweating0
paresthesia0
neuritis0
insomnia0
neutropenia0
allergic reaction0
pain0
otitis media0
palpitations0
abnormal vision0
vomiting0
dry mouth0
peripheral edema0
urinary incontinence0
migraine0
tremor0
toothache0
bone pain0
tinnitus0
thrombocytopenia0
tendinitis0
tachycardia0
syncope0
vertigo0
sinusitis0
chest pain substernal0
malaise0
polyuria0
nausea0
albuminuria0
constipation0
cystitis0
diabetes mellitus0
diarrhea0
somnolence0
dyspepsia0
dyspnea0
eczema0
edema0
conjunctivitis0
chest pain0
bronchitis0
anemia0
angina pectoris0
anorexia0
anxiety0
arthritis0
asthma0
ataxia0
atrial fibrillation0
back pain0
epistaxis0
esophagitis0
fever0
hyperkalemia0
hypersensitivity0
hypokalemia0
hyponatremia0
influenza0
ischemia0
arthrosis0
kidney calculus0
leg cramps0
hyperglycemia0
hypercholesterolemia0
herpes simplex0
flatulence0
flushing0
furunculosis0
gastritis0
gastroenteritis0
gingivitis0
glycosuria0
gout0
hematuria0
leukopenia0

Target

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Uniprot ID:CP2C9_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC9
Cytochrome P450 2C9
P-450MP
P450 MP-4/MP-8
P450 PB-1
S-mephenytoin 4-hydroxylase
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:1OG2 1OG5 1R9O
Structure:
1R9O

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: