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Drug-Target Interaction

Drug

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PubChem ID:5280733
Structure:
Synonyms:
(5S,6E,8Z,11Z,14Z)-5-hydroxyeicosa-6,8,11,14-tetraenoic acid
(5S,6E,8Z,11Z,14Z)-5-hydroxyicosa-6,8,11,14-tetraenoic acid
(6E,8Z,11Z,14Z)-(5S)-5-Hydroxyicosa-6,8,11,14-tetraenoic acid
(S)-(E,Z,Z,Z)-5-hydroxyeicosa-6,8,11,14-tetraenoic acid
5(S)-HETE
5(S)-hydroxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid
5(S)-hydroxyeicosatetraenoic acid
5-HETE
5-Hydroxy-6,8,11,14-eicosatetraenoic acid
5-Hydroxyeicosatetraenoate
5-Hydroxyeicosatetraenoic acid
5S-HETE
6,8,11,14-Eicosatetraenoic acid, 5-hydroxy-, (S-(E,Z,Z,Z))-
70608-72-9
AC1NQXIH
BCBcMAP01_000020
BML1-B01
BSPBio_001443
C04805
CHEBI:28209
CHEMBL164813
HMS1361I05
HMS1791I05
HMS1989I05
IDI1_033913
LMFA03060002
LS-63797
NCGC00161235-01
NCGC00161235-02
NCGC00161235-03

Target

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Uniprot ID:LOX5_HUMAN
Synonyms:
5-lipoxygenase
5-LO
Arachidonate 5-lipoxygenase
EC-Numbers:1.13.11.34
Organism:Homo sapiens
Human
PDB IDs:2ABV
Structure:
2ABV

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--2000-

References: