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Drug-Target Interaction

Drug

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PubChem ID:5280383
Structure:
Synonyms:
()-oxazepam hemisuccinate sodium salt
(5S,6S,7E,9E,11Z,14Z)-5,6-Epoxyicosa-7,9,11,14-tetraenoate
(5S,6S,7E,9E,11Z,14Z)-5,6-epoxyicosa-7,9,11,14-tetraenoic acid
(7E,9E,11Z,14Z)-(5S,6S)-5,6-Epoxyeicosa-7,9,11,14-tetraenoate
(7E,9E,11Z,14Z)-(5S,6S)-5,6-Epoxyeicosa-7,9,11,14-tetraenoic acid
(7E,9E,11Z,14Z)-(5S,6S)-5,6-Epoxyicosa-7,9,11,14-tetraenoate
4-[(2S,3S)-3-[(1E,3E,5Z,8Z)-tetradeca-1,3,5,8-tetraenyl]oxiran-2-yl]butano
5(S)-5,6-oxido-7,9-trans-11,14-cis-eicosatetraenoic acid
5S,6S-epoxy-7E,9E,11Z,14Z-eicosatetraenoic acid
5S,6S-leukotriene A4
72059-45-1
AC1NQWZ2
C00909
CHEBI:15651
CHEMBL69439
Leukotriene A4
LMFA03020023
LTA4
Oxiranebutanoic acid, 3-(1,3,5,8-tetradecatetraenyl)-, (2S-(2alpha,3beta(1E,3Z,5Z,8Z)))-

Target

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Uniprot ID:LOX5_HUMAN
Synonyms:
5-lipoxygenase
5-LO
Arachidonate 5-lipoxygenase
EC-Numbers:1.13.11.34
Organism:Homo sapiens
Human
PDB IDs:2ABV
Structure:
2ABV

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--2000-

References: