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Drug-Target Interaction

Drug

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PubChem ID:5280360
Structure:
Synonyms:
(15S)-Prostaglandin E2
(5Z,11-alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,11.alpha.,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic
(5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dienoic acid
(5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate
(5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate
(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid
(Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
363-24-6
5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-
5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)- (8CI)
5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-,
5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-, l-
7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid
AIDS-003352
AIDS-166064
AIDS003352
AIDS166064
BMS-279654 & PGE2
BSPBio_001490
C00584
C20H32O5
Cervidil
Cervidil (TN)
CHEBI:15551
D00079
Dinoproston
Dinoprostona
Dinoprostona [INN-Spanish]
Dinoprostone
Dinoprostone (JAN/USP/INN)
Dinoprostone [USAN:BAN:INN:JAN]
Dinoprostone [USAN:INN:BAN:JAN]
Dinoprostonum
Dinoprostonum [INN-Latin]
EINECS 206-656-6
Glandin
IDI1_033960
l-7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid
l-PGE2
l-Prostaglandin E2
LMFA03010003
LS-125823
Minprositin E2
Minprostin E2
NCGC00092361-01
NCGC00092361-02
NCGC00092361-03
NCGC00092361-04
NCGC00092361-05
nchembio.106-comp6
nchembio.147-comp12
NSC 165560
NSC 196514
P0409_SIGMA
P5640_SIGMA
P6532_SIGMA
PGE2
PGE2 alpha
PGE2alpha
Prepidil
Prepidil (TN)
Prepidil Gel
Prestwick_793
Propess
Prosta-5,13-dien-1-oic acid, (5Z,11-alpha,13E,15S)-11,15-dihydroxy-9-oxo-
Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5Z,11alpha,13E,15S)-
Prostaglandin E2
Prostaglandin E2 alpha
Prostaglandin E2alpha
Prostin
Prostin E2
Prostin E2 (TN)
SMP2_000056
U 12062
U-12062
ATC-Codes:
Side-Effects:
Side-EffectFrequency
abdominal pain0.0010
vomiting0.0010
fever0.0010
nausea0.0010
diarrhea0.0010
breast tenderness0
vaginitis0
tremor0
tachycardia0
syncope0
pharyngitis0
paresthesia0
weakness0
pain0
nocturnal leg cramps0
hearing loss0
increased sweating0
sepsis0
myalgia0
eye pain0
neck rigidity0
blurred vision0
chills0
urinary retention0
bradycardia0
vulvitis0
wheezing0
myocardial infarction0
dizziness0
dehydration0
cough0
chest pain0
bronchospasm0
back pain0
arthritis0
arthralgia0
arrhythmia0
dyspnea0
endometritis0
rash0
muscle cramps0
laryngitis0
hypotension0
hypertension0
hot flashes0
hiccup0
hemorrhage0
headache0
flushing0
acidosis0

Target

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Uniprot ID:PE2R1_HUMAN
Synonyms:
PGE receptor, EP1 subtype
Prostaglandin E2 receptor EP1 subtype
Prostanoid EP1 receptor
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----
--1.1-

References: