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Drug-Target Interaction

Drug

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PubChem ID:518740
Structure:
Synonyms:
2,4,5-trioxa-1,3-diarsabicyclo[1.1.1]pentane
AC1LAR2Z
Acide Arsenieux [French]
Anhydride Arsenieux [French]
Arseni Trioxydum
ARSENIC (III) OXIDE, ACS
Arsenic Blanc [French]
Arsenic Oxide
Arsenic Oxidearsenous Trioxide
Arsenic Sesquioxide
Arsenic trioxide
Arsenic Trioxide [UN1561] [Poison]
Arsenic(III) oxide
Arsenic, White
Arsenicum Album
Arsenigen Saure [German]
Arsenious Acid
Arsenious Acid Anhydride
Arsenious Oxide
Arsenious Trioxide
Arsenous Acid
Arsenous Acid Anhydride
Arsenous Anhydride
Arsenous Oxide
Arsenous Oxide Anhydride
Arsentrioxide
CID518740
Crude Arsenic
DB01169
Di-Arsenic Trioxide
Diarsenic Trioxide
Diarsonic Trioxide
HSDB 419
Oxyde Arsenieux [ISO-French]
Poison Flour
White Arsenic
ATC-Codes:
Side-Effects:
Side-EffectFrequency
metrorrhagia0
renal failure0
seizures0
sinusitis0
tachycardia0
thrombocytopenia0
tinnitus0
tremor0
erythema0
upper respiratory tract infection0
urinary incontinence0
pruritus0
postnasal drip0
pleural effusion0
nasopharyngitis0
nausea0
neutropenia0
night sweats0
pain0
pain in limb0
palpitations0
weakness0
paresthesia0
petechiae0
urticaria0
vascular disorders0
myalgia0
eye redness0
hypoxia0
sore throat0
sepsis0
dry eyes0
blurred vision0
lymphadenopathy0
ecg abnormal0
increased sweating0
hyperpigmentation0
dry skin0
sgot increased0
vertigo0
vomiting0
weight gain0
weight loss0
wheezing0
dry mouth0
agitation0
vaginal hemorrhage0
hypomagnesemia0
bone pain0
insomnia0
leukocytosis0
abdominal distention0
coma0
confusion0
constipation0
cough0
dermatitis0
diarrhea0
dizziness0
somnolence0
drug hypersensitivity0
dyspepsia0
chest pain0
neck pain0
oral moniliasis0
abdominal pain0
acidosis0
anemia0
anorexia0
anxiety0
arrhythmia0
arthralgia0
back pain0
bacterial infections0
blistering0
dyspnea0
ear pain0
hemorrhage0
herpes simplex0
herpes zoster0
hyperglycemia0
hyperkalemia0
hypertension0
hypocalcemia0
hypoglycemia0
hypokalemia0
hypotension0
hemoptysis0
blood dyscrasia0
heart disease0
ecchymosis0
edema0
epistaxis0
rash0
fatigue0
fecal incontinence0
fever0
flushing0
gastrointestinal hemorrhage0
headache0
infection0

Target

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Uniprot ID:MK03_HUMAN
Synonyms:
ERK-1
ERT2
Extracellular signal-regulated kinase 1
Insulin-stimulated MAP2 kinase
MAP kinase 1
MAPK 1
Microtubule-associated protein 2 kinase
Mitogen-activated protein kinase 3
p44-ERK1
p44-MAPK
EC-Numbers:2.7.11.24
Organism:Homo sapiens
Human
PDB IDs:2ZOQ
Structure:
2ZOQ

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: