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Drug-Target Interaction

Drug

show drug details
PubChem ID:5073
Structure:
Synonyms:
106266-06-2
3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidino)ethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one
3-[2-[-4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperi-dino]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]-pyrimidin-4-one
3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[2,1-b]pyrimidin-4-one
3-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
4H-Pyrido(1,2-a)pyrimidin-4-one,
4H-Pyrido(1,2-a)pyrimidin-4-one, 3-(2-(4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-6 ,7,8,9-tetrahydro-2-methyl-
4H-Pyrido(1,2-a)pyrimidin-4-one, 3-(2-(4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-2-methyl-
4H-Pyrido(1,2-a)pyrimidin-4-one, 6,7,8,9-tetrahydro-3-(2-(4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-2-methyl-
4H-Pyrido[1,2-a]pyrimidin-4-one, 3-[2-[4-(6-fluoro-1,2-benz-isoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-
AB00514010
AIDS-085404
AIDS085404
Ambap6280
Belivon
BRN 4891881
C23H27FN4O2
CAS-106266-06-2
CHEBI:8871
CID5073
Consta, Risperdal
CPD000466323
D00426
D018967
DB00734
EU-0101074
KS-1106
Lopac-R-118
LS-134196
MLS000759429
MLS001165758
MLS001424081
NCGC00015883-01
NCGC00015883-02
NCGC00094352-01
NCGC00094352-02
NCGC00094352-03
NCGC00179257-01
Prestwick0_001029
Prestwick1_001029
R 64 766, Risperdal, Risperidone
R 64,766
R 64766
R-64,766
R-64766
R64,766
R64766
Risperdal
Risperdal (TN)
Risperdal Consta
Risperdal M-Tab
Risperidal
Risperidal M-Tab
Risperidona
Risperidona [Spanish]
RISPERIDONE
Risperidone (JAN/USAN/INN)
Risperidone (RIS)
Risperidone [USAN:BAN:INN]
Risperidone, placebo
Risperidonum
Risperidonum [Latin]
Risperin
Rispolept
Rispolin
SAM001246595
Sequinan
SMR000466323
SPBio_003078
TL8000230
ATC-Codes:
Side-Effects:
Side-EffectFrequency
polydipsia1.0
menorrhagia1.0
polyuria1.0
psychosis1.0
nervousness1.0
amenorrhea0.80200005
dysuria0.505
skeletal pain0.47717655
anemia0.40510005
dyspnea0.375
vomiting0.35750002
hypotension0.35478267
agitation0.3463438
arthralgia0.33400002
back pain0.33040008
chest pain0.30035716
insomnia0.23000002
abdominal pain0.22079545
anxiety0.21592592
photosensitivity0.20799999
rash0.19316675
upper respiratory tract infection0.151
anorexia0.12526314
paralysis0.124
hematuria0.10899999
tetany0.10103449
torticollis0.09458064
constipation0.09285714
bradycardia0.091176465
pain0.08922361
asthenia0.08765259
urinary incontinence0.087025546
nausea0.07993447
somnolence0.07551434
tachycardia0.07328807
abnormal gait0.058999997
ataxia0.058999993
fatigue0.05330474
coughing0.049999993
diarrhea0.047037035
saliva increased0.046955056
pharyngitis0.033809524
dizziness0.03186984
rhinitis0.031743348
parkinsonism0.030964252
dyskinesia0.025999997
dyspepsia0.02433635
tooth disorder0.022857143
weight increase0.0228
confusion0.02190476
dry skin0.02181818
tremor0.021336831
urinary tract infection0.020000001
tooth ache0.015999999
concentration impaired0.015714286
headache0.013141174
mouth dry0.012663468
palpitation0.01230769
epistaxis0.011875002
pruritus0.0111578945
vaginal hemorrhage0.01
intermenstrual bleeding0.01
hypochromic anemia0.01
dysarthria0.01
weight decrease0.01
mastitis0.01
hyperkeratosis0.01
influenza0.01
bronchospasm0.01
sweating0.01
hepatomegaly0.009999999
pneumonia0.009999999
hemorrhoids0.009999999
purpura0.009999999
hemoptysis0.009999999
av block0.009999999
malaise0.009999999
vaginitis0.009999999
hypercholesterolemia0.009999999
stridor0.009999999
bundle branch block0.009999999
hyponatremia0.009999999
irritable bowel syndrome0.009999999
obesity0.009999999
hypothyroidism0.009999999
myocardial ischemia0.009999999
muscle weakness0.009999999
melena0.009999999
phlebitis0.009999999
hyperlipemia0.009999999
vertigo0.009999999
myocardial infarction0.009999999
earache0.009999999
paresthesia0.009999999
eczema0.009999999
colitis0.009999999
dysmenorrhea0.009999999
conjunctivitis0.009999999
abscess0.009999999
convulsions0.009999999
syncope0.009999999
ulcerative stomatitis0.009999999
gastric ulcer0.009999999
stomatitis0.009999999
dysphagia0.009999999
deafness0.009999999
increased sweating0.009999999
tendinitis0.009999999
choking0.009999999
flatulence0.009999999
amnesia0.009999999
gastritis0.009999999
rectal hemorrhage0.009999999
renal pain0.009999999
micturition frequency0.009999999
glycosuria0.009999999
apraxia0.009999999
fever0.009969064
hypotension postural0.009700002
seborrhea0.009545454
vision abnormal0.009411208
arthrosis0.0090
eye pain0.0090
migraine0.008199999
gastroesophageal reflux0.008199999
urinary retention0.008199999
gingivitis0.008199999
angina pectoris0.008199999
dehydration0.008199999
fecal incontinence0.008199999
arthritis0.008199999
hypokalemia0.008199999
dermatitis0.008199999
hearing decreased0.008199999
hyperuricemia0.008199999
lymphadenopathy0.008199999
leg cramps0.008199999
alopecia0.007428571
breast pain0.007428571
delirium0.0069999993
paroniria0.0069999993
myalgia0.0047052596
sinusitis0.0040112315
lactation nonpuerperal0.0036860427
acne0.0023258438
hypertension0.0019199976
diabetes mellitus0.0018265318
impotence0.0017422691
hyperprolactinemia0.0017422691
decreased libido0.0017422689
tardive dyskinesia0.0017422688
hyperglycemia0.0017422688
leukopenia0.0017272738
gynecomastia0.0017128724
granulocytopenia0.0016923079
arrhythmia0.0014615384
edema0.001409092
dementia0.001387098
sgot increased0.0013614458
bipolar disorder0.001000001
strokes0.001000001
thrombopenia0.0010000003
pulmonary embolism0.0010000003
jaundice0.0010000003
apnea0.0010
photophobia0.0010
photopsia0.0010
claudication0.0010
aphasia0.0010
ventricular extrasystoles0.0010
lymphopenia0.0010
allergic reaction0.0010
hepatic failure0.0010
hyperphosphatemia0.0010
choreoathetosis0.0010
renal insufficiency0.0010
verruca0.0010
superficial phlebitis0.0010
tinnitus0.0010
thrombophlebitis0.0010
anaphylactic shock0.0010
urticaria0.0010
angioedema0.0010
suicide attempt0.0010
diabetic ketoacidosis0.0010
cerebrovascular disorder0.0010
hemorrhage0.0010
bilirubinemia0.0010
allergy0.0010
hypertrichosis0.0010
hypertriglyceridemia0.0010
hypoglycemia0.0010
transient ischemic attacks0.0010
inappropriate antidiuretic hormone secretion0.0010
cystitis0.0010
leukocytosis0.0010
bursitis0.0010
myocarditis0.0010
hematoma0.0010
hematemesis0.0010
diplopia0.0010
diverticulitis0.0010
coma0.0010
cachexia0.0010
cholelithiasis0.0010
eructation0.0010
esophagitis0.0010
cholecystitis0.0010
fatty liver0.0010
flushing0.0010
furunculosis0.0010
gastroenteritis0.0010
gi hemorrhage0.0010
hepatitis0.0010
neutropenia0.0010
peripheral nervous system disorders0.0010
premature atrial contractions0.0010
priapism0.0010
psoriasis0.0010
asthma0.0010
sleep apnea0.0010
atrial fibrillation0.0010
pulmonary edema0.0010
schizophrenia0.0010
hyperacusis0.0010
sarcoidosis0.0010
seizures0.0010
ascites0.0010
pancreatitis0.0010
blepharitis0.0010
skin ulceration0.0010
stevens - johnson syndrome0.0010
pituitary adenomas0.001
ventricular tachycardia0.001
manic0
dysphonia0
euphoria0
schizoaffective disorder0
endocrine disorders0
infection0
delusions0
adenomas0
depersonalization0
spasm0
erythema multiforme0
swelling0
clotting0
rhabdomyolysis0
peripheral edema0
viral infection0
leg pain0
emotional lability0
apathy0
otitis media0
stupor0
menstrual disorder0
vestibular disorders0
hypothermia0
retinal artery occlusion0
hallucinations0
thrombotic thrombocytopenic purpura0
thinking abnormal0
elation0
chronic schizophrenic0
tension headache0
vascular disorders0
fungal infection0

Target

show target details
Uniprot ID:Q6XP50_HUMAN
Synonyms:
Cytochrome P450
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: