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Drug-Target Interaction

Drug

show drug details
PubChem ID:5070
Structure:
Synonyms:
1744-22-5
2-amino-6-(trifluoromethoxy)-1,3-benzothiazole
2-Amino-6-(trifluoromethoxy)-benzothiazole
2-Amino-6-(trifluoromethoxy)benzothiazole
2-amino-6-(trifluoromethoxy)benzo[d]thiazole
2-amino-6-(trifluoromethoxyl)benzothiazole
2-Amino-6-trifluoro- methoxybenzothiazole
2-amino-6-trifluoromethoxybenzothiazole
2-Benzothiazolamine, 6-(trifluoromethoxy)-
6-(trifluoromethoxy)-1,3-benzothiazol-2-amine
6-(trifluoromethoxy)benzothiazole-2-ylamine
6-(trifluoromethoxy)benzo[d]thiazol-2-amine
6-Trifluoromethoxy-benzothiazol-2-ylamine
6-trifluoromethoxybenzothiazole-2-yl-amine
AC-730
AC1L1JJL
AC1Q530H
AG-E-24013
AKOS000265071
ALBB-006046
Amino-2 trifluoromethoxy-6 benzothiazole
Amino-2 trifluoromethoxy-6 benzothiazole [French]
BB_SC-4839
BENZOTHIAZOLE, 2-AMINO-6-TRIFLUOROMETHOXY-
BF-37
BIDD:GT0055
Bio1_000416
Bio1_000905
Bio1_001394
Biomol-NT_000245
BPBio1_000037
BPBio1_000837
BRD-K21283037-001-02-5
BRD-K21283037-003-03-9
BSPBio_000033
C07937
C8H5F3N2OS
CCG-39528
CHEMBL744
D00775
DB00740
EU-0101064
FT-0082997
HMS1773G08
HMS2089O19
HMS2094G07
HMS2233E14
HMS3263E10
I01-2084
Lopac-R-116
Lopac0_001064
LS-40688
MLS000069369
NCGC00015882-01
NCGC00015882-02
NCGC00015882-03
NCGC00015882-04
NCGC00015882-05
NCGC00015882-06
NCGC00015882-07
NCGC00015882-08
NCGC00015882-09
NCGC00015882-10
NCGC00015882-11
NCGC00015882-12
NCGC00015882-13
NCGC00023141-02
NCGC00023141-04
NCGC00023141-05
NCGC00023141-06
PK-26124
PK-26124, RP-54274, Rilutek, Riluzole
Prestwick-03A08
Prestwick0_000167
Prestwick1_000167
Prestwick2_000167
Prestwick3_000167
R-116
R116_SIGMA
Rilutek
Rilutek (TN)
Riluzol
Riluzol [INN-Spanish]
Riluzole
Riluzole (JAN/USAN/INN)
Riluzole HCl
Riluzole [USAN:INN]
Riluzole-Supplied by Selleck Chemicals
Riluzolum
Riluzolum [INN-Latin]
RP 54274
RP-54274
S1614_Selleck
SMR000058231
SPBio_000599
SPBio_001954
Spectrum2_000550
ST038494
ST068834
STK503686
Tocris-0768
UNII-7LJ087RS6F
ZERO/001785
ZINC00006481
ATC-Codes:
Side-Effects:
Side-EffectFrequency
agitation1.0
tremor0.5005
asthenia0.16575
nausea0.14899999
rhinitis0.07350001
headache0.07225
dizziness0.06025
abdominal pain0.058750004
anorexia0.052
diarrhea0.051250003
hypertension0.04825
weight loss0.0445
dyspepsia0.043500002
vomiting0.034333333
arthralgia0.034
peripheral edema0.0315
pruritus0.03133333
dry mouth0.02975
insomnia0.02975
urinary tract infection0.029500002
back pain0.028750002
cough0.024999999
vertigo0.0245
flatulence0.0225
somnolence0.02025
tachycardia0.019666666
paresthesia0.015500002
eczema0.010000001
leukocytosis0.01
anemia0.01
lung edema0.01
personality disorder0.01
pericarditis0.01
pneumothorax0.01
weight gain0.01
abscess0.01
chills0.01
fungal dermatitis0.01
myocardial ischemia0.01
confusion0.01
shock0.01
ventricular extrasystoles0.01
angina pectoris0.01
syncope0.01
atrial fibrillation0.01
congestive heart failure0.01
heart failure0.01
seborrhea0.01
bundle branch block0.01
gout0.01
gum hemorrhage0.01
gastritis0.01
leukopenia0.01
sepsis0.01
photosensitivity0.01
sinusitis0.00975
palpitation0.00775
postural hypotension0.0075000003
stomatitis0.0075000003
alopecia0.0070
tooth disorder0.0062499996
oral moniliasis0.0062499996
dysuria0.0062499996
phlebitis0.0062499996
exfoliative dermatitis0.0059999996
subdural hematoma0.0055
hypotension0.0055
hyponatremia0.0055
hypokalemia0.0055
convulsion0.0055
asthma0.0055
hiccup0.0055
skin ulceration0.0055
hernia0.0055
bone neoplasm0.0055
ataxia0.0055
attempted suicide0.0055
stridor0.0055
hemoptysis0.0055
hemiplegia0.0055
hematuria0.0055
hepatitis0.0055
impotence0.0055
amblyopia0.0055
metrorrhagia0.0055
priapism0.0055
prostate carcinoma0.0055
pleural effusion0.0055
lung carcinoma0.0055
peritonitis0.0055
acidosis0.0055
psoriasis0.0055
abnormal gait0.0055
diabetes mellitus0.0055
kidney pain0.0055
flu syndrome0.0055
jaundice0.0055
arthrosis0.0055
kidney calculus0.0055
laryngitis0.0055
leg cramps0.0055
amnesia0.0055
pancreatitis0.0055
hypoxia0.0055
fecal impaction0.0055
coma0.0055
fecal incontinence0.0055
cerebral hemorrhage0.0055
facial paralysis0.0055
urticaria0.0055
migraine0.0055
esophageal stenosis0.0055
dysarthria0.0055
epistaxis0.0055
decreased libido0.0055
embolus0.0055
urinary retention0.0055
ecchymosis0.0055
urinary incontinence0.0055
malaise0.0055
hallucinations0.0055
glossitis0.0055
peripheral vascular disease0.0055
urinary urgency0.0055
thyroid neoplasia0.0055
tenesmus0.0055
gastrointestinal haemorrhage0.0055
cellulitis0.0055
ulceration0.0055
moniliasis0.0040
edema0.0040
neoplasm0.0040
acute brain syndrome0.00325
proctitis0.0010
purpura0.0010
cerebral ischemia0.0010
breast abscess0.0010
polyps0.0010
photophobia0.0010
cataract0.0010
petechiae0.0010
vestibular disorder0.0010
psychosis0.0010
supraventricular tachycardia0.0010
uterine hemorrhage0.0010
subarachnoid hemorrhage0.0010
tetany0.0010
skin nodule0.0010
bradycardia0.0010
lymphadenopathy0.0010
dementia0.0010
uterine fibroids0.0010
iron deficiency anemia0.0010
vascular disorders0.0010
ventricular fibrillation0.0010
hyperacusis0.0010
ventricular tachycardia0.0010
pyelonephritis0.0010
phobia0.0010
artery occlusion0.0010
furunculosis0.0010
enterocolitis0.0010
hypothermia0.0010
infections0.0010
cholecystitis0.0010
hypercalcemia0.0010
angioedema0.0010
vaginal moniliasis0.0010
ear pain0.0010
hypochromic anemia0.0010
erythema multiforme0.0010
rheumatoid arthritis0.0010
glaucoma0.0010
cutaneous moniliasis0.0010
granuloma0.0010
cerebral embolism0.0010
hematemesis0.0010
hemorrhage0.0010
breast disorders0.0010
blepharitis0.0010
hypercholesteremia0.0010
aplastic anemia0.0010
connective tissue disorders0.0010
osteoporosis0.0010
nocturia0.0010
neutropenia0.0010
deafness0.0010
tooth caries0.0010
cysts0.0010
pain0.0010
contact dermatitis0.0010
diabetes insipidus0.0010
breast pain0.0010
mediastinal disorders0.0010
melena0.0010
amenorrhea0.0010
diplopia0.0010
peripheral neuritis0.0010
endocrine disorders0.0010
bone necrosis0.0010
emotional lability0
hyperamylasemia0
chest pain0
dysphagia0
sensory disturbance0
choking0
mouth ulceration0
constipation0
interstitial lung disease0
myalgia0
abdominal pain upper0
agranulocytosis0
gastric carcinoma0
radiculopathy0
white blood cell count increased0
cardiomyopathy0
acute pancreatitis0
eosinophilic pneumonia0
malformations0
allergic alveolitis0
manic0
elevated blood pressure0
disturbance in attention0
thinking abnormal0
bronchitis0
lung neoplasm malignant0
blindness0
apnea0
hypoventilation0
anxiety0
respiratory failure0
apathy0
pain in limb0
pulmonary embolism0
cor pulmonale0
lymphoma0
acute renal failure0
renal failure0
rhabdomyolysis0
hyperlipidemia0
hyperhidrosis0
shoulder pain0
lymphopenia0
methemoglobinemia0
pancytopenia0
peripheral neuropathy0
neuralgia0
nasal congestion0
pneumonia0
lobar pneumonia0
myocardial infarction0
postmenopausal bleeding0
muscle atrophy0
herpes zoster0
hepatitis b0
euphoria0
esophagitis0
myasthenia gravis0
dyspnea0
diabetic ketoacidosis0
drug eruption0
depersonalization0
delusions0
stupor0
rash0
fatigue0
hematoma0
cardiac murmur0
heart disease0
cardiac arrest0
thrombocytopenia0
intestinal functional disorder0
flushing0
loss of consciousness0
fever0
dehydration0

Target

show target details
Uniprot ID:CP1A1_HUMAN
Synonyms:
CYPIA1
Cytochrome P450 1A1
P450 form 6
P450-C
P450-P1
EC-Numbers:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: