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Drug-Target Interaction

Drug

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PubChem ID:4977
Structure:
Synonyms:
.beta.-Hydroxypropyltheophylline
1,3-DIMETHYL-7-(2-HYDROXYPROPYL)-2,6-DIOXOPURINE
1,3-Dimethyl-7-(2-hydroxypropyl)-2,6-dioxopurine]
1,3-Dimethyl-7-(2-hydroxypropyl)xanthine
1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-7-(2-hydroxypropyl)-
1H-Purine-2,6-dione, 3,7-dihydro-7-(2-hydroxypropyl)-1,3-dimethyl-
1H-Purine-2,6-dione, 3,7-dihydro-7-(2-hydroxypropyl)-1,3-dimethyl- (9CI)
2-Hydroxypropyl-7-theophylline
3,7-Dihydro-7-(2-hydroxypropyl)-1,3-dimethyl-1H-purine-2,6-dione
603-00-9
7-(.beta.-Hydroxypropyl)-1,3-dimethylxanthine
7-(.beta.-Hydroxypropyl)theophylline
7-(2-hydroxypropyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
7-(2-hydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
7-(2-hydroxypropyl)-1,3-dimethylpurine-2,6-dione
7-(2-Hydroxypropyl)theophylline
7-(beta-Hydroxypropyl)-1,3-dimethylxanthine
7-(beta-HYDROXYPROPYL)-THEOPHYLLINE
7-(beta-Hydroxypropyl)theophylline
AB00513948
AC1L1JCF
AC1Q2BVZ
AC1Q2BW0
AC1Q6LE8
AR-1L2503
beta-Oxypropyltheophyllin
BPBio1_000748
BRD-A28887267-001-03-7
Brontyl
BSPBio_000680
C10H14N4O3
CHEBI:153737
CHEMBL37390
D01771
EINECS 210-028-7
HMS1570B22
HMS2097B22
HMS2233E08
Hydroxypropyltheophylline
LS-149606
MLS000069521
Monophyllin
Monophyllin (TN)
Monophylline
MT
NCGC00018121-02
NCGC00018121-03
NCGC00179479-01
NSC 163343
NSC163343
Oxypropyltheophylline
PDSP1_001132
PDSP2_001116
Prestwick0_000890
Prestwick1_000890
Prestwick2_000890
Prestwick3_000890
Proxifilina
Proxifilina [INN-Spanish]
Proxiphylline
Proxiphyllinum
Proxy-Retardoral
Proxyphyline
PROXYPHYLLINE
Proxyphylline (JAN/INN)
Proxyphylline [BAN:INN:JAN]
Proxyphylline [INN:BAN:JAN]
proxyphylline(jan)
Proxyphyllinum
Proxyphyllinum [INN-Latin]
Purophyllin
Sanwaphyllin
Sigophyl
SMR000058629
Spasmolysin
SPBio_002899
ST5409303
Thean
Theoden
Theon
Theophylline, 7-(2-hydroxypropyl)-
UNII-13G1DMN4P0
ATC-Codes:

Target

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Uniprot ID:PDE5A_HUMAN
Synonyms:
CGB-PDE
cGMP-binding cGMP-specific phosphodiesterase
cGMP-specific 3',5'-cyclic phosphodiesterase
EC-Numbers:3.1.4.35
Organism:Homo sapiens
Human
PDB IDs:1RKP 1T9R 1T9S 1TBF 1UDT 1UDU 1UHO 1XOZ 1XP0 2CHM 2H40 2H42 2H44 3B2R 3BJC 3HC8 3HDZ
Structure:
3HDZ

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
600000---

References: