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Drug-Target Interaction

Drug

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PubChem ID:4923
Structure:
Synonyms:
1-[amino-(4-chloroanilino)methylidene]-2-propan-2-ylguanidine
1-[amino-[(4-chlorophenyl)amino]methylidene]-2-propan-2-ylguanidine
AC1L1J8U
DB01131
Proguanil
ATC-Codes:
Side-Effects:
Side-EffectFrequency
diarrhea0.18888888
headache0.18857142
abdominal pain0.17333333
nausea0.1575
dizziness0.085
insomnia0.083333336
fever0.07857143
myalgia0.074999996
oral ulcers0.0675
cough0.0675
vomiting0.061249997
flu syndrome0.044
upper respiratory infection0.042000003
back pain0.04
pruritus0.035
dyspepsia0.024999999
anxiety0.023333333
gastritis0.016666666

Target

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Uniprot ID:CP3A4_HUMAN
Synonyms:
Albendazole monooxygenase
Albendazole sulfoxidase
CYPIIIA3
CYPIIIA4
Cytochrome P450 3A3
Cytochrome P450 3A4
HLp
NF-25
Nifedipine oxidase
P450-PCN1
Quinine 3-monooxygenase
Taurochenodeoxycholate 6-alpha-hydroxylase
EC-Numbers:1.14.13.32
1.14.13.67
1.14.13.97
Organism:Homo sapiens
Human
PDB IDs:1TQN 1W0E 1W0F 1W0G 2J0D 2V0M
Structure:
2V0M

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: