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Drug-Target Interaction

Drug

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PubChem ID:4915
Structure:
Synonyms:
1-Methyl-2-(p-(isopropylcarbamoyl)benzyl)hydrazine
2-(p-Isopropylcarbamoylbenzyl)-1-methylhydrazine
366-70-1
366-70-1 (mono-hydrochloride)
4-((2-Methylhydrazino)methyl)-N-isopropylbenzamide
4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide
671-16-9
AC-4547
AC1L1J8E
Ambap6381
Ambap671-16-9
Benzamide, N-(1-methylethyl)-4-((2-methylhydrazino)methyl)-
Benzamide, N-(1-methylethyl)-4-((2-methylhydrazino)methyl)- (9CI)
Benzamide, N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]-
BIDD:GT0183
BPBio1_001369
BRN 0958270
BSPBio_001244
C07402
C12H19N3O
CAS-366-70-1
CB 400-497
CCRIS 2389
CHEMBL1321
D08423
DB01168
EINECS 211-582-2
HMS2090J09
HSDB 3250
I01-8931
Ibenzmethyzin
Ibenzmethyzine
Ibenzmethyzine hydrochloride
IBZ
LS-7671
MBH
MIH
MIH Hydrochloride
N-(1-Methylethyl)-4-((2-methylhydrazino)methyl)benzamide
N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]benzamide
N-4-Isopropylcarbamoylbenzyl-N'-methylhydrazine
N-isopropyl-4-[(2-methylhydrazino)methyl]benzamide
N-Isopropyl-alpha-(2-methylhydrazino)-p-toluamide
N-Isopropyl-p-(2-methylhydrazinomethyl)-benzamide
Natulan
Natulanar
NCGC00016438-01
NCGC00016438-02
NCI60_041703
NCIOpen2_004074
NSC-77213
p-(2-Methylhydrazinomethyl)-N-isopropylbenzamide
p-(N'-Methylhydrazinomethyl)-N-isopropylbenzamide
p-Toluamide, N-isopropyl-.alpha.-(2-methylhydrazino)-
p-Toluamide, N-isopropyl-alpha-(2-methylhydrazino)-
PCB
PCB hydrochloride
PCX
Prestwick0_001112
Prestwick1_001112
Prestwick2_001112
Prestwick3_001112
Procarbazin
Procarbazin [German]
Procarbazina
Procarbazina [INN-Spanish]
Procarbazine
Procarbazine (INN)
Procarbazine hydrochloride
Procarbazine Monohydrochloride
Procarbazine [INN:BAN]
Procarbazinum
Procarbazinum [INN-Latin]
Ro 4-6467
Ro 4-6467/1
SPBio_003112
SRI-10847
UNII-35S93Y190K
ZINC19166988
ATC-Codes:
Side-Effects:
Side-EffectFrequency
acute myelocytic leukemia0.0010
papilledema0.0010
weakness0.0010
paresthesia0.0010
pericarditis0.0010
petechiae0.0010
pleural effusion0.0010
pneumonitis0.0010
pruritus0.0010
purpura0.0010
pancytopenia0.0010
pancreatitis0.0010
leukopenia0.0010
melena0.0010
myelosclerosis0.0010
nausea0.0010
nervousness0.0010
nightmares0.0010
nocturia0.0010
nystagmus0.0010
pain0.0010
retinal hemorrhage0.0010
stomatitis0.0010
sweating0.0010
photosensitivity0.0010
neuropathy0.0010
osteonecrosis0.0010
urinary frequency0.0010
lung cancer0.0010
diaphoresis0.0010
insomnia0.0010
hearing loss0.0010
bleeding tendencies0.0010
myalgia0.0010
hyperpigmentation0.0010
fainting0.0010
tachycardia0.0010
thrombopenia0.0010
tremors0.0010
urticaria0.0010
vomiting0.0010
dry mouth0.0010
chills0.0010
photophobia0.0010
allergic reactions0.0010
jaundice0.0010
alopecia0.0010
constipation0.0010
convulsions0.0010
cough0.0010
dysphagia0.0010
dermatitis0.0010
diarrhea0.0010
diplopia0.0010
dizziness0.0010
drowsiness0.0010
confusion0.0010
coma0.0010
anemia0.0010
hemolytic anemia0.0010
angina0.0010
abdominal pain0.0010
anorexia0.0010
arthralgia0.0010
ascites0.0010
ataxia0.0010
malignancies0.0010
edema0.0010
eosinophilia0.0010
toxic epidermal necrolysis0.0010
hoarseness0.0010
herpes0.0010
hypotension0.0010
infections0.0010
hemoptysis0.0010
hematuria0.0010
hematemesis0.0010
headache0.0010
hallucinations0.0010
epistaxis0.0010
rash0.0010
fatigue0.0010
pyrexia0.0010
flushing0.0010
gynecomastia0.0010
hypertension0.0010
lymphocytosis0
amenorrhea0
hypersensitivity0
arrhythmia0
apprehension0
neutropenia0
hemorrhage0
leukemia0
constitutional symptoms0
sterility0

Target

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Uniprot ID:CP1A2_HUMAN
Synonyms:
CYPIA2
Cytochrome P450 1A2
P(3)450
P450 4
P450-P3
EC-Numbers:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:2HI4
Structure:
2HI4

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: