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Drug-Target Interaction

Drug

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PubChem ID:480764
Structure:
Synonyms:
(-)-(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)chroman-4
(-)-(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)chroman-4-one
(-)-(2S)-8-dimethylallylnaringenin
(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-chromen-4-one
(S)-8-dimethylallylnaringenin
5,7-Dihydroxy-2-(4-hydroxy-phenyl)-8-(3-methyl-but-2-enyl)-1-benzopyran-4-one
8-Prenylnaringenin
8-prenylnaringenin (8-PN)
AC1LA3DM
AIDS-095901
AIDS095901
BIDD:ER0149
C18023
CHEBI:50207
CHEMBL376915
Flavaprenin
sophoraflavanone B
YS04
ZINC00039452

Target

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Uniprot ID:PDE5A_HUMAN
Synonyms:
CGB-PDE
cGMP-binding cGMP-specific phosphodiesterase
cGMP-specific 3',5'-cyclic phosphodiesterase
EC-Numbers:3.1.4.35
Organism:Homo sapiens
Human
PDB IDs:1RKP 1T9R 1T9S 1TBF 1UDT 1UDU 1UHO 1XOZ 1XP0 2CHM 2H40 2H42 2H44 3B2R 3BJC 3HC8 3HDZ
Structure:
3HDZ

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--16230-

References: