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Drug-Target Interaction

Drug

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PubChem ID:4708
Structure:
Synonyms:
3968-03-4
4-anilinoquinazoline deriv. 2
4-[(3-Bromophenyl)amino]-6-acrylamidoquinazoline
AC1L1IRY
AC1Q26CC
AR-1K4749
CHEMBL285063
CID4708
DB07662
HSCI1_000120
IN1166
N-(4-(3-Bromophenylamino)quinazolin-6-yl)acrylamide
N-[4-(3-bromoanilino)quinazolin-6-yl]prop-2-enamide
n-{4-[(3-bromophenyl)amino]quinazolin-6-yl}prop-2-enamide
nchembio866-comp2
PD 168393
PD-168393
ZINC01488208

Target

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Uniprot ID:ERBB2_HUMAN
Synonyms:
C-erbB-2
CD340
MLN 19
NEU proto-oncogene
p185erbB2
Receptor tyrosine-protein kinase erbB-2
Tyrosine kinase-type cell surface receptor HER2
EC-Numbers:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1MFG 1MFL 1MW4 1N8Z 1OVC 1QR1 1S78 2A91 2JWA 3BE1
Structure:
3BE1

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--5.7-
--24-

References: