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Drug-Target Interaction

Drug

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PubChem ID:4708
Structure:
Synonyms:
3968-03-4
4-anilinoquinazoline deriv. 2
4-[(3-Bromophenyl)amino]-6-acrylamidoquinazoline
AC1L1IRY
AC1Q26CC
AR-1K4749
CHEMBL285063
CID4708
DB07662
HSCI1_000120
IN1166
N-(4-(3-Bromophenylamino)quinazolin-6-yl)acrylamide
N-[4-(3-bromoanilino)quinazolin-6-yl]prop-2-enamide
n-{4-[(3-bromophenyl)amino]quinazolin-6-yl}prop-2-enamide
nchembio866-comp2
PD 168393
PD-168393
ZINC01488208

Target

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Uniprot ID:EGFR_HUMAN
Synonyms:
Epidermal growth factor receptor
Receptor tyrosine-protein kinase ErbB-1
EC-Numbers:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1DNQ 1DNR 1IVO 1M14 1M17 1MOX 1NQL 1XKK 1YY9 1Z9I 2EB2 2EB3 2EXP 2EXQ 2GS2 2GS6 2GS7 2ITN 2ITO 2ITP 2ITQ 2ITT 2ITU 2ITV 2ITW 2ITX 2ITY 2ITZ 2J5E 2J5F 2J6M 2JIT 2JIU 2JIV 2RF9 2RFD 2RFE 2RGP 3B2U 3B2V 3BEL 3BUO 3C09 3GOP 3GT8
Structure:
3GT8

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--0.7-
--0.70-
--<1.5-
--1.69-
--2-
--2-
--2.7-
--4.3-
--12-
--36-
--152-

References: