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Drug-Target Interaction

Drug

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PubChem ID:4679
Structure:
Synonyms:
102625-70-7
1H-Benzimidazole,
1H-Benzimidazole, 5-(difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridinyl)methyl)sulfinyl)-
1H-Benzimidazole, 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-
5-(Difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridyl)methyl)sulfinyl)benzimidazole
5-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1H-benzimidazole
BSPBio_002320
BY 1023
BY-1023
C11806
C16H15F2N3O4S
CHEBI:7915
D05353
DB00213
HSDB 7292
LS-32883
NCGC00095188-01
NCGC00095188-02
NCGC00095188-03
Pantoloc
Pantopan
Pantoprazol
Pantoprazol [INN-Spanish]
Pantoprazole
Pantoprazole (USAN/INN)
Pantoprazole Na
Pantoprazole Sodium
Pantoprazole [USAN:BAN:INN]
Pantoprazolum
Pantoprazolum [INN-Latin]
Pantoprozole
Pantozol
Protium
Protonix
Protonix IV
SK&F 96022
SK&F-96022
SKF-96022
SL-00656
SPECTRUM1505818
TL8000127
ATC-Codes:
Side-Effects:
Side-EffectFrequency
headache0.055714287
diarrhea0.027999997
abdominal pain0.02
liver function tests abnormal0.015
hyperglycemia0.0066666664
flatulence0.0038500011
insomnia0.0028499996
vomiting0.002055555
nausea0.0017916658
rash0.0016750001
eructation0.0014210527
vertigo0.0010
urticaria0.0010
paresthesia0.0010
tremor0.0010
tinnitus0.0010
rhabdomyolysis0.0010
thrombophlebitis0.0010
thrombocytopenia0.0010
stevens - johnson syndrome0.0010
increased salivation0.0010
dry mouth0.0010
allergic reactions0.0010
hyperuricemia0.0010
acne0.0010
neuropathy0.0010
photosensitivity0.0010
blurred vision0.0010
upper abdominal pain0.0010
myalgia0.0010
malaise0.0010
peripheral edema0.0010
photophobia0.0010
hepatic failure0.0010
pancytopenia0.0010
alopecia0.0010
toxic epidermal necrolysis0.0010
eosinophilia0.0010
edema0.0010
somnolence0.0010
dizziness0.0010
exfoliative dermatitis0.0010
mental depression0.0010
constipation0.0010
arthralgia0.0010
angioedema0.0010
erythema multiforme0.0010
esophagitis0.0010
increased body temperature0.0010
pancreatitis0.0010
nervousness0.0010
interstitial nephritis0.0010
leukopenia0.0010
jaundice0.0010
impotence0.0010
elevated triglycerides0.0010
hypercholesterolemia0.0010
gerd0.0010
hematuria0.0010
hallucination0.0010
anaphylactic reactions0.001
confusion0.001
migraine0
carcinoma0
urethritis0
ecchymosis0
dysphagia0
diplopia0
palpitations0
dysmenorrhea0
muscle cramps0
vaginitis0
tendinitis0
voice alteration0
rhinitis0
periodontitis0
dysarthria0
neuritis0
sinus congestion0
infection0
nasal congestion0
sinusitis0
sweating0
laryngitis0
ulcerative stomatitis0
stomatitis0
dry skin0
moniliasis0
hyperlipidemia0
enteritis0
vascular disorders0
iron deficiency anemia0
sgot increased0
ulcerative colitis0
influenza0
urinary frequency0
cataract0
glaucoma0
tachycardia0
dermatitis0
congestive heart failure0
neck pain0
breast pain0
balanitis0
cyst0
toothache0
tonsillitis0
tenosynovitis0
abscess0
gastric polyps0
leukocytosis0
upper respiratory tract infection0
arthritis0
halitosis0
melena0
leg cramps0
dysuria0
thinking abnormal0
emotional lability0
hypotension0
glossitis0
sepsis0
epistaxis0
hepatitis0
hemorrhage0
gastritis0
amblyopia0
laboratory test abnormal0
dehydration0
abdominal distention0
goiter0
dyspnea0
abnormal vision0
otitis externa0
cholelithiasis0
angina pectoris0
osteoarthritis0
neck rigidity0
periodontal abscess0
elation0
deafness0
cholecystitis0
chest pain0
sleep disorder0
blood dyscrasia0
colitis0
epididymitis0
pain0
dyspareunia0
pain in limb0
decreased libido0
albuminuria0
herpes simplex0
syncope0
tumor0
anorexia0
atrial fibrillation0
glycosuria0
eczema0
gastroenteritis0
neuralgia0
arrhythmia0
erythema0
back pain0
ear pain0
rectal hemorrhage0
bilirubinemia0
myocardial infarction0
contact dermatitis0
kidney pain0
hematemesis0
urinary tract infection0
hypertension0
seizures0
chest pain substernal0
pruritus0
bone pain0
pyelonephritis0
anemia0
ecg abnormal0
bursitis0
myocardial ischemia0
duodenitis0
oral moniliasis0
gastrointestinal hemorrhage0
mouth ulceration0
paralysis0
herpes zoster0
anxiety0
arthrosis0
glossodynia0
viral infection0
lung disorder0
hypochromic anemia0
cystitis0
weight loss0
gout0
weight gain0
diabetes mellitus0
asthma0
bloating0
gingivitis0
pneumonia0
fungal dermatitis0
chills0
cough0
hypersensitivity0
skin ulcer0
alkaline phosphatase increased0
hemorrhoids0
elevated blood pressure0
bronchitis0
hiccup0
asthenia0
nasopharyngitis0
pharyngitis0
fatigue0
nocturia0
hernia0

Target

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Uniprot ID:CP2CJ_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC17
CYPIIC19
Cytochrome P450 2C19
Mephenytoin 4-hydroxylase
P450-11A
P450-254C
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: