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Drug-Target Interaction

Drug

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PubChem ID:461195
Structure:
Synonyms:
2,3-Dihydro-9-methoxy[1]benzothieno[2,3-f]-1,4-thiazepin-5(4H)-one
9-methoxy-3,4-dihydro-2H-[1]benzothiolo[2,3-f][1,4]thiazepin-5-one
AC1LA3S9
AIDS-028464
AIDS028464
CHEBI:265295
CHEMBL319170
CID461195
PD-146626
PD146626

Target

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Uniprot ID:MAPK2_HUMAN
Synonyms:
MAP kinase-activated protein kinase 2
MAPK-activated protein kinase 2
MAPKAP kinase 2
MAPKAPK-2
MK2
EC-Numbers:2.7.11.1
Organism:Homo sapiens
Human
PDB IDs:1KWP 1NXK 1NY3 2JBO 2JBP 2OKR 2ONL 2OZA 2P3G 2PZY 3FPM 3FYJ 3FYK
Structure:
3FYK

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--1090-
--5500-

References: