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Drug-Target Interaction

Drug

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PubChem ID:4601
Structure:
Synonyms:
2-(Phenyl-o-tolylmethoxy)ethyldimethylamine
2-Methyldiphenhydramine
341-69-5
341-69-5 (hydrochloride)
4-06-00-04727 (Beilstein Handbook Reference)
4682-36-4
4682-36-4 (citrate)
83-98-7
AB00053510
AC1L1IJ4
Antiflex
beta-Dimethylaminoethyl 2-methylbenzhydryl ether
beta-Dimethylaminoethyl-2-methylbenzhydryl ether
Biorphen
BPBio1_000349
BRD-A53576514-003-03-1
BRN 1885151
Brocadisipal
Brocasipal
BS 5930
BSPBio_000317
BSPBio_002141
C07935
C18H23NO
CBDivE_006102
CCG-204966
CHEBI:177779
CHEBI:7789
CHEMBL900
D08305
DB01173
Disipal
DivK1c_000853
EINECS 201-509-2
Ethanamine, N,N-dimethyl-2-((2-methylphenyl)phenylmethoxy)-
Ethanamine, N,N-dimethyl-2-[(2-methylphenyl)phenylmethoxy]-
Ethylamine, N,N-dimethyl-2-((o-methyl-alpha-phenylbenzyl)oxy)-
HSDB 3139
IDI1_000853
KBio1_000853
KBio2_001525
KBio2_004093
KBio2_006661
KBio3_001641
KBioGR_000880
KBioSS_001525
L001253
Lopac0_000884
LS-68148
Lysantin
Mefenamine
Mephenamine
Methyldiphenylhydramine
Mialgin (TN)
Mio-Rel
Myolin
Myotrol
N,N-Dimethyl-2-(alpha-2-tolylbenzoyloxy)ethylamin
N,N-dimethyl-2-(alpha-2-tolylbenzoyloxy)ethylamine
N,N-Dimethyl-2-(o-methyl-alpha-phenylbenzyl)oxy)ethylamine
N,N-Dimethyl-2-[(2-methylphenyl)(phenyl)methoxy]ethanamine
N,N-dimethyl-2-[(2-methylphenyl)-phenylmethoxy]ethanamine
N,N-Dimethyl-2-[(o-methyl-alpha-phenylbenzyl)oxy]ethylamine
N,N-dimethyl-2-{[(2-methylphenyl)(phenyl)methyl]oxy}ethanamine
NCGC00015771-03
NCGC00015771-04
NCGC00015771-05
NCGC00015771-06
NCGC00015771-07
NCGC00015771-09
NCGC00015771-10
NCGC00089814-02
NCGC00089814-03
NCGC00089814-04
NCGC00089814-05
NINDS_000853
Norflex
Norflex Orphenadrine Citrate
o-Methyldiphenhydramine
o-Monomethyldiphenhydramine
Oprea1_476547
Orfenadrina
Orfenadrina [INN-Spanish]
Orfro
ORP
Orphenadine
Orphenadinum
Orphenadrin
Orphenadrine
Orphenadrine (INN)
Orphenadrine Citrate
Orphenadrine hydrochloride
Orphenadrine [INN:BAN]
Orphenadrinum
Orphenadrinum [INN-Latin]
Orphenate
Orphenedrine
Phenyl-o-tolylmethyl dimethyaminoethyl ether
Prestwick0_000239
Prestwick1_000239
Prestwick2_000239
Prestwick3_000239
Sodium Mefenamine
SPBio_001255
SPBio_002238
Spectrum2_001038
Spectrum3_000531
Spectrum4_000460
Spectrum5_001036
Spectrum_001045
ST50406606
ST5406606
UNII-AL805O9OG9
WS 2434
Side-Effects:
Side-EffectFrequency
anaphylaxis0
weakness0
pruritus0
tachycardia0
tremor0
urticaria0
vomiting0
agitation0
urinary hesitancy0
palpitations0
nausea0
aplastic anemia0
confusion0
constipation0
dizziness0
somnolence0
hallucinations0
headache0
hypersensitivity0
blurred vision0

Target

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Uniprot ID:CP2CJ_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC17
CYPIIC19
Cytochrome P450 2C19
Mephenytoin 4-hydroxylase
P450-11A
P450-254C
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: