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Drug-Target Interaction

Drug

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PubChem ID:4595
Structure:
Synonyms:
(RS)-1,2,3,9-Tetrahydro-9-methyl-3-(2-methylimidazol-1-ylmethyl)carbazol-4-one
1,2,3,9-Tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-4H-carba
1,2,3,9-Tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-4H-carbazol-4-one
103639-04-9
108303-49-7
116002-70-1
4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-
9-Methyl-3-(2-methyl-imidazol-1-ylmethyl)-1,2,3,9-tetrahydro-carbazol-4-one
9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one
9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one
99614-01-4
99614-02-5
AB00373674
BAS 00717177
BB_SC-1124
BPBio1_001118
BRN 3622981
BSPBio_001016
C07325
C18H19N3O
CBDivE_008994
D00456
DB00904
GR 38032
GR 38032X
GR-38032F
GR38032F
LS-172305
LS-51878
NCI60_022780
Ondansetron
Ondansetron (JAN/USP/INN)
ondansetron (Zofran)
ONDANSETRON HYDROCHLORIDE
Ondansetron [USAN:INN:BAN]
Ondansetron, (+,-)-Isomer
Oprea1_435466
Oprea1_852372
Prestwick0_001058
Prestwick1_001058
Prestwick2_001058
Prestwick3_001058
SN-307
SPBio_002938
STK370548
TimTec1_001750
TL8006071
Zofran
ZOFRAN IN PLASTIC CONTAINER
Zofran ODT
Zofran ODT (TN)
ZOFRAN PRESERVATIVE FREE
Zophren
Zudan
ATC-Codes:
Side-Effects:
Side-EffectFrequency
headache0.15679899
drowsiness0.14006934
musculoskeletal pain0.10410519
fatigue0.094711296
malaise0.09471127
hypoxia0.08401517
diarrhea0.08056486
constipation0.073151514
dizziness0.06561335
bradycardia0.05787879
fever0.056153648
agitation0.049797885
anxiety0.049797878
urinary retention0.04165283
hypotension0.041169617
pruritus0.036746923
chest pain0.022582654
dysuria0.019424973
pain0.018705212
paresthesia0.014771492
bronchospasm0.009940465
tachycardia0
allergic reaction0
syncope0
ventricular extrasystoles0
stridor0
stevens - johnson syndrome0
supraventricular tachycardia0
tremor0
blindness0
shortness of breath0
dry mouth0
blurred vision0
second degree heart block0
hepatic failure0
urticaria0
myocardial ischemia0
shock0
seizures0
heart block0
grand mal0
toxic epidermal necrolysis0
edema0
abdominal pain0
dyskinesia0
atrial fibrillation0
arrhythmia0
angioedema0
angina pectoris0
rash0
flushing0
weakness0
palpitations0
myocardial infarction0
movement disorders0
mediastinal disorders0
liver disease0
hypokalemia0
hypersensitivity0
hiccup0
anaphylaxis0

Target

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Uniprot ID:CP2C9_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC9
Cytochrome P450 2C9
P-450MP
P450 MP-4/MP-8
P450 PB-1
S-mephenytoin 4-hydroxylase
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:1OG2 1OG5 1R9O
Structure:
1R9O

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----

References: