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Drug-Target Interaction

Drug

show drug details
PubChem ID:4585
Structure:
Synonyms:
10H-Thieno(2,3-b)(1,5)benzodiazepine, 2-methyl-4-(4-methyl-1-piperazinyl)-
10H-thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(4-methyl-1-piperazinyl)-
132539-06-1
2-Methyl-4-(4-methyl-1-piperazinyl)- 10H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methyl-1-piperazinyl)-10 H -thieno[2,3- b ]
2-methyl-4-(4-methyl-1-piperazinyl)-10 H -thieno[2,3- b ] [1,5]benzodiazepine
2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine
2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[3,2-c][1,5]benzodiazepine
AB1008596
AC-665
AC1L1IHS
AIDS-191113
AIDS191113
AKOS000282888
ALKS-7921
BB_SC-5093
BIDD:GT0332
BIDD:PXR0138
Bio-0169
C07322
C076029
C17H20N4S
CCG-100922
CHEBI:7735
CHEMBL1671891
CHEMBL715
CID4585
CPD000466345
D00454
DB00334
Eli Lilly brand of olanzapine
HMS2051H05
HMS2089M04
HMS2093I04
HMS2233F24
I06-0784
Jsp001969
KS-1090
KVWDHTXUZHCGIO-UHFFFAOYSA-
L000455
L005958
Lanzac
Lilly brand of olanzapine
LS-152313
LY 170053
LY-170052
LY-170053
Midax
Mixture Name
MLS000759457
MLS001165781
MLS001195646
MLS001424057
MolPort-003-666-569
NCGC00096077-01
NCGC00096077-03
NCGC00096077-04
Olansek
olanzapina
Olanzapine
Olanzapine (JAN/USAN/INN)
Olanzapine (OLA)
Olanzapine [USAN:INN]
Olanzapine, Zyprexa, Zalasta, Zolafren, Olzapin, Oferta, Zypadhera
Olanzapine-Supplied by Selleck Chemicals
olanzapinum
S2493_Selleck
SAM001246652
SMR000466345
SPECTRUM1505024
STK634338
Symbyax
TL8000772
UNII-N7U69T4SZR
Zalasta
Zydis
Zyprexa
Zyprexa (TN)
Zyprexa Intramuscular
Zyprexa Velotab
ZYPREXA ZYDIS
ATC-Codes:
Side-Effects:
Side-EffectFrequency
flu syndrome1.0
pain1.0
joint stiffness1.0
dental pain1.0
conjunctivitis1.0
flatulence0.604
amenorrhea0.406
leukopenia0.406
hematuria0.406
metrorrhagia0.406
suicide attempt0.406
vaginitis0.3907692
hypotension0.3642857
increased salivation0.35999998
dyspnea0.3460001
sweating0.3453335
paresthesia0.26775
libido decreased0.2625
somnolence0.23228075
amnesia0.18944442
dry mouth0.11813954
insomnia0.115555555
asthenia0.09775509
dizziness0.090588234
parkinsonism0.08799999
weight gain0.08235293
dyspepsia0.07666667
diarrhea0.072
constipation0.066666655
tremor0.06641508
rhinitis0.06555555
personality disorder0.0525
back pain0.048947368
cough0.046666667
amblyopia0.046470582
ecchymosis0.04111111
extremity pain0.04111111
joint pain0.038333338
abnormal gait0.03272727
peripheral edema0.030799996
pharyngitis0.030624997
nausea0.030000001
fever0.026473686
vomiting0.02642857
postural hypotension0.022916667
confusion0.022000002
movement disorder0.02
chest pain0.019285714
tachycardia0.019090908
choreoathetosis0.0175
dyskinesia0.017499998
urinary tract infection0.015555554
urinary incontinence0.015555554
hypertension0.015454545
sleep disorder0.015
spasm0.015
torticollis0.015
tooth disorder0.015
impotence0.015
edema0.014666666
tardive dyskinesia0.013333332
neck rigidity0.012222221
ear pain0.01142857
joint disorder0.01142857
menorrhagia0.01
dry eyes0.01
pelvic pain0.01
rectal hemorrhage0.01
malaise0.01
periodontal abscess0.01
alkaline phosphatase increased0.01
eye pain0.01
pneumonia0.01
palpitation0.01
abdominal pain0.01
hyperuricemia0.01
acne0.01
urinary frequency0.01
otitis media0.01
dementia0.01
lymphadenopathy0.01
bradycardia0.01
photosensitivity0.01
phobias0.01
aspiration pneumonia0.01
polyuria0.01
mouth ulceration0.01
syncope0.01
thrombocytopenia0.01
tinnitus0.01
cataract0.01
urinary retention0.01
voice alteration0.01
abnormal vision0.01
vertigo0.01
somatization0.01
stuttering0.01
cerebrovascular accident0.01
premenstrual syndrome0.01
pruritus0.01
pyuria0.01
vaginal hemorrhage0.01
ventricular extrasystoles0.01
seborrhea0.01
skin ulcer0.01
migraine0.01
stomatitis0.01
uterine fibroids0.01
melena0.01
acidosis0.01
diabetes mellitus0.01
diplopia0.01
dysarthria0.01
dysmenorrhea0.01
dysuria0.01
eczema0.01
epistaxis0.01
av block0.01
facial paralysis0.01
fecal incontinence0.01
fecal impaction0.01
gastritis0.01
gastroenteritis0.01
gingivitis0.01
contact dermatitis0.01
tooth caries0.01
alopecia0.01
apnea0.01
arthritis0.01
asthma0.01
ataxia0.01
blepharitis0.01
moniliasis0.01
oral moniliasis0.01
neck pain0.01
cystitis0.01
deafness0.01
dysphagia0.01
dehydration0.01
delirium0.01
glycosuria0.01
laryngitis0.01
hemorrhage0.01
leg cramps0.01
hepatitis0.01
bilirubinemia0.01
hypercholesteremia0.01
hyperglycemia0.01
hyperlipemia0.01
hypoglycemia0.01
hypokalemia0.01
hyponatremia0.01
hemoptysis0.01
heart block0.01
congestive heart failure0.01
heart arrest0.01
breast pain0.01
leukocytosis0.01
dry skin0.009999999
chills0.0066249995
urinary urgency0.0063999994
hypoxia0.0063999994
esophagitis0.0063999994
atrial fibrillation0.0063999994
urticaria0.0063999994
gynecomastia0.0063999994
anemia0.005499999
rash0.005499999
thrombocythemia0.0046
eructation0.0046
bursitis0.0046
atelectasis0.0046
coma0.0046
hyperkalemia0.0035714286
myopathy0.0010
stridor0.0010
nystagmus0.0010
paralysis0.0010
albuminuria0.0010
neuralgia0.0010
mastitis0.0010
rheumatoid arthritis0.0010
neuropathy0.0010
arteritis0.0010
hypoventilation0.0010
osteoporosis0.0010
hypopigmentation0.0010
liver fatty0.0010
heart failure0.0010
hypernatremia0.0010
glaucoma0.0010
glossitis0.0010
aphthous stomatitis0.0010
subarachnoid hemorrhage0.0010
goiter0.0010
gout0.0010
pulmonary embolus0.0010
enteritis0.0010
esophageal ulcer0.0010
keratoconjunctivitis0.0010
bone pain0.0010
breast enlargement0.0010
encephalopathy0.0010
diabetic acidosis0.0010
hirsutism0.0010
hiccup0.0010
lung edema0.0010
menstrual disorder0
hallucinations0
abscess0
myalgia0
anxiety0
neutropenia0
headache0
stupor0
thinking abnormal0
depersonalization0
emotional lability0
apathy0
delusions0
euphoria0
manic0
pancreatitis0
angioedema0
seizures0
deep vein thrombosis0
fungal dermatitis0
fatigue0
schizoaffective disorder0
neurosis0
rhabdomyolysis0
allergic reaction0
weight loss0
nervousness0
sgot increased0
drug dependence0
anorexia0
priapism0
jaundice0

Target

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Uniprot ID:CP2C9_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC9
Cytochrome P450 2C9
P-450MP
P450 MP-4/MP-8
P450 PB-1
S-mephenytoin 4-hydroxylase
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:1OG2 1OG5 1R9O
Structure:
1R9O

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: