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Drug-Target Interaction

Drug

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PubChem ID:4553
Structure:
Synonyms:
123653-11-2
AC1L1IF7
AC1Q20LP
AR-1K3665
Bio2_000472
Bio2_000952
BRD-K53364951-001-02-6
BSPBio_001264
C080955
C13H18N2O5S
CCRIS 8523
CHEBI:101699
CHEMBL7162
HMS1362P05
HMS1792P05
HMS1990P05
I14-10018
IDI1_002227
IN1319
KBio2_000604
KBio2_003172
KBio2_005740
KBio3_001067
KBio3_001068
KBioGR_000604
KBioSS_000604
LS-90104
Methanesulfonamide, N-(2-(cyclohexyloxy)-4-nitrophenyl)-
N-(2-Cyclohexyloxy-4-nitrophenyl)methanesulfonamide
N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide
N194_SIGMA
NCGC00024892-01
NCGC00024892-02
NCGC00024892-03
nchembio.147-comp10
NS 398
NS-398
NS398
NS4
Tocris-0942
ZINC03791739

Target

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Uniprot ID:PGH1_SHEEP
Synonyms:
COX-1
Cyclooxygenase-1
PGH synthase 1
PGHS-1
PHS 1
Prostaglandin G/H synthase 1
Prostaglandin H2 synthase 1
Prostaglandin-endoperoxide synthase 1
EC-Numbers:1.14.99.1
Organism:Ovis aries
Sheep
PDB IDs:1CQE 1DIY 1DJJ 1EBV 1EQG 1EQH 1FE2 1HT5 1HT8 1IGX 1IGZ 1PGE 1PGF 1PGG 1PRH 1PTH 1Q4G 1U67 2AYL 2OYE 2OYU
Structure:
2OYU

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--14100-
-->20000-
--37000-

References: