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Drug-Target Interaction

Drug

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PubChem ID:4542
Structure:
Synonyms:
13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetrade
17-ethynyl-17-hydroxy-18a-homoestr-4-en-3-one
18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (17.alpha.)-(.+/-.)-
6533-00-2
CHEBI:7630
LD norgestrel
Methylnorethindrone
Norgestrel
Norgestrelum
Oprea1_224559
Side-Effects:
Side-EffectFrequency
hypertrichosis0.0010
oligomenorrhea0.0010
otitis media0.0010
ovarian cyst0.0010
pain0.0010
pelvic pain0.0010
pharyngitis0.0010
pneumonia0.0010
polyps0.0010
ectopic pregnancy0.0010
pruritis0.0010
rhinitis0.0010
nervousness0.0010
neoplasm0.0010
infections0.0010
influenza0.0010
leg pain0.0010
mastitis0.0010
breast pain0.0010
mediastinal disorders0.0010
chloasma0.0010
menstrual disorder0.0010
intermenstrual bleeding0.0010
musculoskeletal pain0.0010
nausea0.0010
sciatica0.0010
seborrhoea0.0010
sinusitis0.0010
fibroadenoma of breast0.0010
lactation nonpuerperal0.0010
iud complication0.0010
pelvic inflammatory disease0.0010
micturition frequency0.0010
breast cancer0.0010
sweating increased0.0010
acne0.0010
abdominal bloating0.0010
dyspareunia0.0010
breast neoplasm0.0010
dry skin0.0010
vaginal bleeding0.0010
tendonitis0.0010
tooth disorder0.0010
toothache0.0010
upper respiratory tract infection0.0010
urinary incontinence0.0010
urinary tract infection0.0010
urticaria0.0010
uterine fibroid0.0010
vertigo0.0010
weight increase0.0010
migraine0.0010
allergic reaction0.0010
hypertension0.0010
abdominal pain0.0010
cystitis0.0010
cysts0.0010
libido decreased0.0010
diarrhea0.0010
dizziness0.0010
cervicitis0.0010
dysmenorrhea0.0010
dysuria0.0010
edema0.0010
connective tissue disorders0.0010
vaginal discharge0.0010
alopecia0.0010
amenorrhea0.0010
angioedema0.0010
arrhythmia0.0010
asthma0.0010
back pain0.0010
breast disorders0.0010
bronchitis0.0010
candidiasis0.0010
endocrine disorders0.0010
endometriosis0.0010
eczema0.0010
headache0.0010
bleeding0.0010
haemorrhoids0.0010
cardiac disorders0.0010
fatigue0.0010
rash0.0010
hirsutism0.0010
fever0.0010
allergy0.0010
endometritis0.0010
anemia0
hypomenorrhea0
depressed mood0
hematuria0
hematoma0
acute appendicitis0
emotional lability0
polydipsia0
weight loss0
lightheadedness0
chest pain0
myalgia0
hypochromic anemia0
herpes simplex0
anorexia0
insomnia0
tearfulness0
menorrhagia0
breast tenderness0
leg cramps0
asthenia0
menometrorrhagia0
anxiety0
vulvovaginitis0
dermatitis0
contact dermatitis0
polymenorrhea0
purpura0
somnolence0
numbness0
dyspepsia0
dyspnea0
abdominal distention0
papilloma0
palpitations0
syncope0
fungal infection0
tonsillitis0
vomiting0
abnormal vision0
pms0
varicose vein0
vaginitis0
constipation0
corpus luteum cyst0
cough0
ulcer0
folliculitis0
flatulence0
otitis0

Target

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Uniprot ID:PRGR_HUMAN
Synonyms:
Nuclear receptor subfamily 3 group C member 3
PR
Progesterone receptor
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:1A28 1E3K 1SQN 1SR7 1ZUC 2C7A 2OVH 2OVM 2W8Y 3D90
Structure:
3D90

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: