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Drug-Target Interaction

Drug

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PubChem ID:449054
Structure:
Synonyms:
()-oxazepam hemisuccinate sodium salt
1vjy
2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine
2-[3-(6-methylpyridin-2-yl)-2H-pyrazol-4-yl]-1,5-naphthyridine
2-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine
446859-33-2
AC1L9MO3
ALK5 Inhibitor II
CHEBI:406655
CHEMBL185238
CID449054
EN002636
HMS3261N03
IN1052
NCGC00242054-01
TGF-beta RI Kinase Inhibitor II
Transforming Growth Factor-beta Type I Receptor Kinase Inhibitor II

Target

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Uniprot ID:MK10_HUMAN
Synonyms:
c-Jun N-terminal kinase 3
MAP kinase p49 3F12
Mitogen-activated protein kinase 10
Stress-activated protein kinase JNK3
EC-Numbers:2.7.11.24
Organism:Homo sapiens
Human
PDB IDs:1JNK 1PMN 1PMQ 1PMU 1PMV 2B1P 2EXC 2O0U 2O2U 2OK1 2P33 2R9S 2WAJ 2ZDT 2ZDU 3CGF 3CGO 3DA6 3FI2 3FI3 3FV8 3G90 3G9L 3G9N
Structure:
3G9N

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
-->16000-

References: