Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug-Target Interaction

Drug

show drug details
PubChem ID:449021
Structure:
Synonyms:
AC1L9MML
ARR
CHEBI:193178
CHEBI:47216
CHEMBL293212
CID449021
DB03449
N'-[4-[2-[(3-chlorophenyl)methylamino]ethyl]phenyl]thiophene-2-carboximida
N'-[4-[2-[(3-chlorophenyl)methylamino]ethyl]phenyl]thiophene-2-carboximidamide
N-(4-(2-((3-CHLOROPHENYLMETHYL)AMINO)ETHYL)PHENYL)-2-THIOPHECARBOXAMIDINE
N-(4-{2-[(3-CHLOROBENZYL)AMINO]ETHYL}PHENYL)THIOPHENE-2-CARBOXIMIDAMIDE

Target

show target details
Uniprot ID:NOS2_MOUSE
Synonyms:
Inducible NO synthase
Inducible NOS
iNOS
MAC-NOS
Macrophage NOS
Nitric oxide synthase, inducible
NOS type II
EC-Numbers:1.14.13.39
Organism:Mouse
Mus musculus
PDB IDs:1DD7 1DF1 1DWV 1DWW 1DWX 1JWJ 1JWK 1M8D 1M8E 1M8H 1M8I 1M9T 1N2N 1NOC 1NOD 1NOS 1QOM 1QW4 1QW5 1R35 1VAF 2BHJ 2NOD 2NOS 2ORO 2ORP 2ORQ 2ORR 2ORS 2ORT 3DWJ 3E65 3E67 3E68 3E6L 3E6N 3E6O 3E6T 3E7I 3E7M 3E7T 3EAI 3EBD 3EBF 3NOD
Structure:
3NOD

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----

References: