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Drug-Target Interaction

Drug

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PubChem ID:447961
Structure:
Synonyms:
(4-(2-Amino-4-methylthiazol-5-yl)pyrimidin-2-yl)-(3-nitrophenyl)amine
1pxo
2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 32
2c5p
4-methyl-5-[2-(3-nitroanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine
AC1L9LFS
Cdk2/9 Inhibitor
CHEBI:167781
CHEBI:41499
CHEMBL298445
CID447961
CK7
DB02833
HMS3229D17
IN1368
ZINC03942776
[4-(2-AMINO-4-METHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-(3-NITRO-PHENYL)-AMINE

Target

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Uniprot ID:STK6_HUMAN
Synonyms:
Aurora kinase A
Aurora-A
Aurora-related kinase 1
Aurora/IPL1-related kinase 1
Breast tumor-amplified kinase
hARK1
Serine/threonine kinase 15
Serine/threonine-protein kinase 6
EC-Numbers:2.7.11.1
Organism:Homo sapiens
Human
PDB IDs:1MQ4 1MUO 1OL5 1OL6 1OL7 2BMC 2C6D 2C6E 2DWB 2J4Z 2J50 2NP8 2W1C 2W1D 2W1E 2W1F 2W1G 3COH 3E5A 3EFW 3FDN 3H0Y 3H0Z 3H10 3HA6
Structure:
3HA6

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
73---

References: