Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug-Target Interaction

Drug

show drug details
PubChem ID:447873
Structure:
Synonyms:
1pmq
AC1L9LC4
CHEMBL437747
CID447873
CYCLOHEXYL-{4-[5-(3,4-DICHLOROPHENYL)-2-PIPERIDIN-4-YL-3-PROPYL-3H-IMIDAZO
CYCLOHEXYL-{4-[5-(3,4-DICHLOROPHENYL)-2-PIPERIDIN-4-YL-3-PROPYL-3H-IMIDAZOL-4-YL]-PYRIMIDIN-2-YL}AMINE
DB02388
imidazole-pyrimidine compound 2
Kinome_3484

Target

show target details
Uniprot ID:MK10_HUMAN
Synonyms:
c-Jun N-terminal kinase 3
MAP kinase p49 3F12
Mitogen-activated protein kinase 10
Stress-activated protein kinase JNK3
EC-Numbers:2.7.11.24
Organism:Homo sapiens
Human
PDB IDs:1JNK 1PMN 1PMQ 1PMU 1PMV 2B1P 2EXC 2O0U 2O2U 2OK1 2P33 2R9S 2WAJ 2ZDT 2ZDU 3CGF 3CGO 3DA6 3FI2 3FI3 3FV8 3G90 3G9L 3G9N
Structure:
3G9N

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----
--1.6-
--2-

References: