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Drug-Target Interaction

Drug

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PubChem ID:44259
Structure:
Synonyms:
(+)-Staurosporine
(5S,6R,7R,9R)-6-methoxy-5-methyl-7-methylamino-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-one
109189-95-9
1nvr
1q3d
1sm2
1stc
1u59
1xbc
1xjd
1yhs
2dq7
2gcd
308079-78-9
62996-74-1
8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one,
8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-
9,13-Epoxy-1H,9H-diindolo(1,2,3-gh:3',2',1'-lm)pyrrolo(3,4-j)(1,7)-benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, (9S-(9alpha,10beta,11beta,13alpha)-
9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, (9S,10R,11R,13R)- & Tumor necrosis factor (TNF)
AIDS-001539
AIDS001539
Alkaloid AM-2282 from Streptomyces
AM-2282
Antibiotic 230
Antibiotic AM 2282
Bio1_000264
Bio1_000753
Bio1_001242
BSPBio_001146
CBiol_001978
CCRIS 3272
CGP 39360
CHEBI:15738
LS-64042
MEGxm0_000307
MolMap_000047
NCGC00162400-01
NCGC00162400-02
NCGC00162400-03
nchembio.162-comp3
NChemBio.2007.20-comp19
nchembio.87-comp4
nchembio809-comp4
QTL1_000078
Staurosporin
STAUROSPORINE
Staurosporine & TNF
Staurosporine & Tumor necrosis factor (TNF)
STO
STU

Target

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Uniprot ID:KS6A5_HUMAN
Synonyms:
90 kDa ribosomal protein S6 kinase 5
Nuclear mitogen- and stress-activated protein kinase 1
Ribosomal protein S6 kinase alpha-5
RSK-like protein kinase
RSKL
EC-Numbers:2.7.11.1
Organism:Homo sapiens
Human
PDB IDs:1VZO
Structure:
1VZO

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
-20--

References: