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Drug-Target Interaction

Drug

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PubChem ID:441233
Structure:
Synonyms:
(1R)-2-phenylcyclopropan-1-amine
155-09-9
AC1L9ASR
C07155
D08625
DB00752
Parnate
Tranylcypromine
Tranylcypromine (INN)
ATC-Codes:
Side-Effects:
Side-EffectFrequency
insomnia0
thrombocytopenia0
tachycardia0
spasm0
scleroderma0
paresthesia0
weakness0
palpitations0
numbness0
tinnitus0
tremor0
urinary incontinence0
memory loss0
urinary frequency0
manic0
blurred vision0
chills0
urinary retention0
dry mouth0
urticaria0
nausea0
leukopenia0
constipation0
confusion0
ataxia0
anxiety0
anorexia0
anemia0
alopecia0
agranulocytosis0
cystic acne0
diarrhea0
dizziness0
siadh0
impotence0
hepatitis0
blood dyscrasia0
headache0
rash0
edema0
somnolence0
abdominal pain0

Target

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Uniprot ID:AOFB_HUMAN
Synonyms:
Amine oxidase [flavin-containing] B
MAO-B
Monoamine oxidase type B
EC-Numbers:1.4.3.4
Organism:Homo sapiens
Human
PDB IDs:1GOS 1H8R 1OJ9 1OJA 1OJB 1OJC 1OJD 1S2Q 1S2Y 1S3B 1S3E 2BK3 2BK4 2BK5 2BYB 2C64 2C65 2C66 2C67 2C70 2C72 2C73 2C75 2C76 2V5Z 2V60 2V61 2VRL 2VRM 2VZ2
Structure:
2VZ2

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----
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References: