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Drug-Target Interaction

Drug

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PubChem ID:441140
Structure:
Synonyms:
(+)-Griseofulvin
(2S)-trans-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2[3H],1'-[2]cyclohexene)-3,4'-dione
(2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione
(2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,
(2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
(2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methylbenzofuran-2-spiro-1'-cyclohex-2'-ene-3,4'-dione
(2S-trans)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione
(2S-trans)-7-chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione
126-07-8
46309_FLUKA
46309_RIEDEL
5-18-05-00150 (Beilstein Handbook Reference)
7-chloro-2',4,6-trimethoxy-6'-beta-spiro[benzofuran-2(3H ),1'-(2)cyclohexene-3,4'-dione]
7-chloro-2',4,6-trimethoxy-6'-beta-spiro[benzofuran-2(3H),1'-(2)cyclohexene-3,4'-dione]
7-Chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3H),1',- [2]cyclohexene]-3,4'-dione
7-chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3H),1'-cyclohexene]-3,4'-dione
7-Chloro-2',4,6-trimethoxy-6'beta-methylspiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione
7-Chloro-4,6,2'-trimethoxy-6'-methylgris-2'-en-3,4'-dione
7-chloro-4,6-dimethox ycoumaran-3-one-2-spiro-1'-(2'-methoxy)-6'-methylcyclohex-2'-en-4'-one
7-chloro-4,6-dimethoxycoumaran-3-one-2-spiro-1'-(2'-methoxy)-6'-methylcyclohex-2'-en-4'-one
7-Chloro-4,6-dimethoxycoumaran-3-one-2-spiro-1'-(2'-methoxy-6'-methylcyclohex-2'-en-4'-one)
7-Chloro-4,6-dimethoxycoumaran-3-one-2-spiro-1-(2'-methoxy-6'-methyl cyclohex-2'-en-4'-one)
ACon0_000953
ACon1_001843
AI3-51015
AIDS-007959
AIDS007959
Amudane
BB_NC-0702
BIM-0051396.0001
Biogrisin-FP
BPBio1_000299
BRN 0095226
BSPBio_000271
BSPBio_001621
C17H17ClO6
Caswell No. 471B
CCRIS 320
CHEBI:27779
curling fact or
Curling factor
DB00400
Delmofulvina
DivK1c_000154
DivK1c_006432
EINECS 204-767-4
EPA Pesticide Chemical Code 471400
Fulcin
Fulcine
Fulvican grisactin
Fulvicin
Fulvicin Bolus (Veterinary)
FULVICIN P/G
FULVICIN P/G 165
FULVICIN P/G 330
Fulvicin-P/G
Fulvicin-U-F
Fulvicin-U/F
Fulvicin-U/F (Veterinary)
Fulvidex (Veterinary)
Fulvina
Fulvine
Fulvinil
Fulvistatin
Fungivin
G2664_SIAL
G4753_SIGMA
Greosin
Gresfeed
Gricin
Grifulin
Grifulvin
Grifulvin V
Gris-PEG
Grisactin
GRISACTIN ULTRA
Griscofulvin
Grise ostatin
Grisefuline
Griseo
GRISEOFULVIN
Griseofulvin forte
Griseofulvin [USAN:BAN:INN:JAN]
Griseofulvin [USAN:INN:BAN:JAN]
GRISEOFULVIN, MICROCRYSTALLINE
GRISEOFULVIN, ULTRAMICROCRYSTALLINE
Griseofulvin-forte
Griseofulvina
Griseofulvina [INN-Spanish]
Griseofulvine
Griseofulvine [INN-French]
Griseofulvinum
Griseofulvinum [INN-Latin]
Griseomix
Griseostatin
Grisetin
Grisofulvin
Grisovin
Grizeofulvin
Grysio
Guservin
HSDB 1722
IDI1_000154
interacts with polymerized microtubules and associated proteins
KBio1_000154
KBio1_001376
KBio2_001296
KBio2_003864
KBio2_006432
KBio3_001121
KBioGR_001454
KBioSS_001296
Lamoryl
Likuden
LMPK13060001
LS-702
MEGxm0_000184
Mixture Name
MLS001304062
MLS002152905
MLS002154239
Murfulvin
NCGC00091120-01
NCGC00091120-02
NCGC00091120-03
NCGC00091120-04
NCGC00091120-05
NCGC00091120-06
NCGC00091120-07
Neo-fulcin
NINDS_000154
NSC 34533
NSC34533
Poncyl
Prestwick3_000226
Prestwick_247
SDCCGMLS-0066450.P001
SMR000718755
SPBio_000225
SpecPlus_000336
SPECTRUM200046
Spectrum2_000213
Spectrum3_000161
Spectrum4_000927
Spectrum5_000648
Spectrum_000816
Spiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, 7-chloro-2',4,6-trimethoxy- 6'-beta-methyl-
Spiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-beta-methyl-
Spiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'S-trans)-
Spiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (2S-trans)-
Spiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-dione, 7-chloro-2'4,6-trimethoxy-6'-beta-methyl-
Spirofulvin
sporostatin
ULTRAGRIS-165
ULTRAGRIS-330
USAF SC-2
ZINC00622123
ATC-Codes:

Target

show target details
Uniprot ID:CP1A2_HUMAN
Synonyms:
CYPIA2
Cytochrome P450 1A2
P(3)450
P450 4
P450-P3
EC-Numbers:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:2HI4
Structure:
2HI4

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: